SLC24A1

Gene Symbol SLC24A1
Entrez Gene 9187
Alt Symbol CSNB1D, HsT17412, NCKX, NCKX1, RODX
Species Human
Gene Type protein-coding
Description solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
Other Description Na(+)/K(+)/Ca(2+)-exchange protein 1|retinal rod Na+/Ca+/K+ exchanger|sodium/potassium/calcium exchanger 1|solute carrier family 24 member 1
Swissprots O75184 Q17RM9 O43485 O60721
Accessions EAW77739 EAW77740 EAW77741 O60721 AB014602 BAA31677 AF026132 AAB97832 AF062921 AAC16732 AF062922 AAC77912 AI026072 AK300633 BAG62323 AK304006 BAG64922 BC012630 BC029407 BC117263 AAI17264 BC143375 AAI43376 BM129630 BM681488 EL947516 EL948740 XM_005254778 XP_005254835 XM_005254781 XP_005254838 XM_006720764 XP_006720827 XM_006720767 XP_006720830 XM_006720768 XP_006720831 XM_006720769 XP_006720832 XM_011522219 XP_011520521 XM_011522220 XP_011520522 XM_011522221 XP_011520523 XM_011522222 XP_011520524 XM_011522223 XP_011520525 XM_011522225 XP_011520527 XM_011522226 XP_011520528 NM_001254740 NP_001241669 NM_001301031 NP_001287960 NM_001301032 NP_001287961 NM_001301033 NP_001287962 NM_004727 NP_004718
Function Critical component of the visual transduction cascade, controlling the calcium concentration of outer segments during light and darkness. Light causes a rapid lowering of cytosolic free calcium in the outer segment of both retinal rod and cone photoreceptors and the light-induced lowering of calcium is caused by extrusion via this protein which plays a key role in the process of light adaptation. Transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+). {ECO:0000269|PubMed:10608890}.
Subcellular Location Membrane; Multi-pass membrane protein.
Tissue Specificity Expressed in the retina, particularly in the inner segment, outer and inner nuclear layers, and ganglion cell layer. {ECO:0000269|PubMed:20850105}.
Top Pathways Phototransduction

Human SLC24A1 protein fragment - ab160373 from Abcam

Category Protein
Source Wheat germ
Species Human
ab160373 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Recombinant Human SLC24A1 Protein - H00009187-Q01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

SLC24A1-Antibody-N-term-Blocking-Peptide - BP16099a from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

SLC24A1 Blocking Peptide - 33R-2672 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

NCKX1 Blocking Peptide - abx063563 from Abbexa

Category Peptide
Species Human, Mouse, Monkey

SLC24A1 - H00009187-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

SLC24A1 - H00009187-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

NCKX1 Blocking Peptide - CBP2369 from Cohesion Biosciences

Category Peptide
Prices $100.00, $300.00
Sizes 1 mg, 5 mg
Species Human, Mouse, Monkey

SLC24A1 Peptide - BS5815P from Bioworld Technology

Category Peptide
Prices $158.00
Sizes 100 µl

SLC24A1 Protein - NBP1-92397PEP from Novus Biologicals

Category Protein
Prices $209.00
Sizes 100 µl
Species Human

SLC24A1 Peptide, Human - M34GP14400H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

Sodium/potassium/calcium exchanger 1 (SLC24A1), Recombinant Protein - MBS7029846 from MyBioSource

Category Protein
Prices $1,110.00, $2,100.00, $3,305.00
Sizes 10 µg, 50 µg, 100 µg
Source E Coli

Sodium/potassium/calcium exchanger 1 (SLC24A1), Recombinant Protein - MBS7057051 from MyBioSource

Category Protein
Source E Coli or Yeast or Baculovirus or Mammalian Cell

Sodium/potassium/calcium exchanger 1 (SLC24A1), Recombinant Protein - MBS1027534 from MyBioSource

Category Protein
Source E Coli or Yeast or Baculovirus or Mammalian Cell

Sodium/potassium/calcium exchanger 1 (SLC24A1), partial, Recombinant Protein - MBS1208685 from MyBioSource

Category Protein
Prices $1,375.00, $1,835.00
Sizes 1 mg (E-Coli), 1 mg (Yeast)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human

SLC24A1 peptide - orb218232 from Biorbyt

Category Peptide
Species Human
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