SLC24A1

Gene Symbol SLC24A1
Entrez Gene 9187
Alt Symbol CSNB1D, HsT17412, NCKX, NCKX1, RODX
Species Human
Gene Type protein-coding
Description solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
Other Description Na(+)/K(+)/Ca(2+)-exchange protein 1|retinal rod Na+/Ca+/K+ exchanger|sodium/potassium/calcium exchanger 1|solute carrier family 24 member 1
Swissprots O75184 Q17RM9 O43485 O60721
Accessions EAW77739 EAW77740 EAW77741 O60721 AB014602 BAA31677 AF026132 AAB97832 AF062921 AAC16732 AF062922 AAC77912 AI026072 AK300633 BAG62323 AK304006 BAG64922 BC012630 BC029407 BC117263 AAI17264 BC143375 AAI43376 BM129630 BM681488 EL947516 EL948740 XM_005254778 XP_005254835 XM_005254781 XP_005254838 XM_006720764 XP_006720827 XM_006720767 XP_006720830 XM_006720768 XP_006720831 XM_006720769 XP_006720832 XM_011522219 XP_011520521 XM_011522220 XP_011520522 XM_011522221 XP_011520523 XM_011522222 XP_011520524 XM_011522223 XP_011520525 XM_011522225 XP_011520527 XM_011522226 XP_011520528 NM_001254740 NP_001241669 NM_001301031 NP_001287960 NM_001301032 NP_001287961 NM_001301033 NP_001287962 NM_004727 NP_004718
Function Critical component of the visual transduction cascade, controlling the calcium concentration of outer segments during light and darkness. Light causes a rapid lowering of cytosolic free calcium in the outer segment of both retinal rod and cone photoreceptors and the light-induced lowering of calcium is caused by extrusion via this protein which plays a key role in the process of light adaptation. Transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+). {ECO:0000269|PubMed:10608890}.
Subcellular Location Membrane; Multi-pass membrane protein.
Tissue Specificity Expressed in the retina, particularly in the inner segment, outer and inner nuclear layers, and ganglion cell layer. {ECO:0000269|PubMed:20850105}.
Top Pathways Phototransduction

NCKX1 CRISPR/Cas9 KO Plasmid (h) - sc-409735 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NCKX1 HDR Plasmid (h) - sc-409735-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NCKX1 Double Nickase Plasmid (h) - sc-409735-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NCKX1 Double Nickase Plasmid (h2) - sc-409735-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NCKX1 CRISPR Activation Plasmid (h) - sc-409735-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NCKX1 CRISPR Activation Plasmid (h2) - sc-409735-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NCKX1 Lentiviral Activation Particles (h) - sc-409735-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NCKX1 Lentiviral Activation Particles (h2) - sc-409735-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NCKX1 siRNA (h) - sc-61158 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NCKX1 shRNA Plasmid (h) - sc-61158-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NCKX1 shRNA (h) Lentiviral Particles - sc-61158-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SLC24A1 RNAi - H00009187-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU076031 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN19477 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19477 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR11184 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr11184

SLC24A1 siRNA (Human) - CRH6080 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SLC24A1 - MBS8208794 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human Slc24a1 (NM_004727.2) - SHH409308 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human SLC24A1(NM_004727.2) - SHL001934 from Creative biogene

Category siRNA
Species Reactivities Human

Human SLC24A1 siRNA - orb266582 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SLC24A1 shRNA Plasmid (Human) - CHH6080 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

SLC24A1 miRNA 3'UTR clone - MiUTR1H-09469 from Creative biogene

Species Reactivities Human
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