Rps6ka5

Gene Symbol	Rps6ka5
Entrez Gene	73086
Alt Symbol	3110005L17Rik, 6330404E13Rik, AI854034, MSK1, MSPK1, RLPK
Species	Mouse
Gene Type	protein-coding
Description	ribosomal protein S6 kinase, polypeptide 5
Other Description	90 kDa ribosomal protein S6 kinase 5|RLSK|RSK-like protein kinase|S6K-alpha-5|nuclear mitogen- and stress-activated protein kinase 1|ribosomal protein S6 kinase alpha-5
Swissprots	Q8C050 Q8CI92
Accessions	EDL18894 EDL18895 EDL18896 EDL18897 Q8C050 AK013999 AK018114 AK030051 AK032316 BAC27809 AK046319 AK135786 AK160758 BAE35993 AY341873 AAQ24158 AY341881 AAQ24165 BC035298 AAH35298 BC038372 XM_006516274 XP_006516337 XM_006516275 XP_006516338 XM_006516276 XP_006516339 NM_153587 NP_705815
Function	Serine/threonine-protein kinase that is required for the mitogen or stress-induced phosphorylation of the transcription factors CREB1 and ATF1 and for the regulation of the transcription factors RELA, STAT3 and ETV1/ER81, and that contributes to gene activation by histone phosphorylation and functions in the regulation of inflammatory genes. Phosphorylates CREB1 and ATF1 in response to mitogenic or stress stimuli such as UV-C irradiation, epidermal growth factor (EGF) and anisomycin. Plays an essential role in the control of RELA transcriptional activity in response to TNF and upon glucocorticoid, associates in the cytoplasm with the glucocorticoid receptor NR3C1 and contributes to RELA inhibition and repression of inflammatory gene expression. In skeletal myoblasts is required for phosphorylation of RELA at 'Ser-276' during oxidative stress. In erythropoietin-stimulated cells, is necessary for the 'Ser-727' phosphorylation of STAT3 and regulation of its transcriptional potential. Phos
Subcellular Location	Nucleus {ECO:0000250}.
Top Pathways	Bladder cancer, MAPK signaling pathway, Neurotrophin signaling pathway, Circadian entrainment, TNF signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones

Mouse-Rps6ka5-Antibody-C-term - AP20900c from Abgent, a WuXi AppTec company Prices $99.00, $295.00 Sizes 80 µl, 400 µl Host Rabbit Clonality Polyclonal

Mouse-Rps6ka5-Antibody-C-term - AP20901c from Abgent, a WuXi AppTec company Prices $99.00, $295.00 Sizes 80 µl, 400 µl Host Rabbit Clonality Polyclonal

Mouse-Rps6ka5-Antibody-C-term - AW5466 from Abgent, a WuXi AppTec company Prices $110.00, $325.00 Sizes 80 µl, 400 µl Host Rabbit Clonality Polyclonal

MSK1 antibody - 70R-35517 from Fitzgerald Prices $275.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

MSK1 antibody - 70R-32692 from Fitzgerald Prices $275.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

MSK1 antibody - 70R-36095 from Fitzgerald Prices $275.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

MSK1 antibody - 70R-34279 from Fitzgerald Prices $275.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

MSK1 antibody (Thr581) - 70R-37032 from Fitzgerald Prices $275.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

MSK1 antibody (Ser212) - 70R-32691 from Fitzgerald Prices $275.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

MSK1 antibody (Ser376) - 70R-34278 from Fitzgerald Prices $275.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Ribosomal Protein S6 Kinase, 90Kda, Polypeptide 5 Antibody - abx115275 from Abbexa Host Rabbit Clonality Polyclonal

RPS6KA5 Antibody - CSB-PA020468GA01HU from Cusabio Host Rabbit

Mouse Rps6ka5 Antibody (C-term) - WA1471 from WuXi Biosciences Prices $110.00, $315.00 Sizes 40 µl, 200 µl Host Rabbit Clonality Polyclonal

Rps6ka5 Antibody - C-terminal region (OAAB18860) - OAAB18860 from Aviva Systems Biology Prices $289.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Rps6ka5 Antibody - C-terminal region (OAAB18861) - OAAB18861 from Aviva Systems Biology Prices $289.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Rps6ka5 Antibody - C-terminal region (OAAB19336) - OAAB19336 from Aviva Systems Biology Prices $289.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Mouse-Rps6ka5-Antibody-C-term - AP21376b from Abgent, a WuXi AppTec company Prices $99.00, $295.00 Sizes 80 µl, 400 µl Host Rabbit Clonality Polyclonal

MSK1 antibody - 70R-50695 from Fitzgerald Prices $475.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Rps6ka5, Polyclonal Antibody - MBS9204496 from MyBioSource Prices $155.00, $340.00 Sizes 80 µl, 400 µl Host Rabbit Clonality Polyclonal

Rps6ka5, Polyclonal Antibody - MBS9211498 from MyBioSource Prices $155.00, $340.00 Sizes 80 µl, 400 µl Host Rabbit Clonality Polyclonal

Rps6ka5, Polyclonal Antibody - MBS9214837 from MyBioSource Prices $155.00, $340.00 Sizes 80 µl, 400 µl Host Rabbit Clonality Polyclonal

anti-MSK1 antibody - ARG51178 from Arigo Biolaboratories Host Rabbit Clonality Polyclonal

anti-MSK1 phospho (Thr581) antibody - ARG20085 from Arigo Biolaboratories Host Rabbit Clonality Polyclonal

ANTI-MOUSE RPS6KA5 (C-TERM) antibody produced in rabbit - SAB1302341 from Sigma-Aldrich Prices $336.50 Sizes 400 µl Clonality Polyclonal

Mouse Rps6ka5 antibody - C - terminal region (OAAB11480) - OAAB11480 from Aviva Systems Biology Host Rabbit Clonality Polyclonal

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