IL1RAPL1

Gene Symbol IL1RAPL1
Entrez Gene 11141
Alt Symbol IL1R8, IL1RAPL, MRX10, MRX21, MRX34, OPHN4, TIGIRR-2
Species Human
Gene Type protein-coding
Description interleukin 1 receptor accessory protein-like 1
Other Description IL-1-RAPL-1|IL-1RAPL-1|IL1RAPL-1|X-linked interleukin-1 receptor accessory protein-like 1|interleukin 1 receptor-8|interleukin-1 receptor accessory protein-like 1|mental retardation, X-linked 10|oligophrenin-4|three immunoglobulin domain-containing IL-1 receptor-related 2
Swissprots A0AVG4 Q9NZN1 Q9UJ53
Accessions BAC80450 BAC80451 BAC80452 BAC80453 BAC80454 BAC80455 BAC80456 BAC80457 BAC80458 BAC80459 BAC80460 BAC80461 BAC80462 BAC80463 BAC80464 BAC80465 BAC80466 BAC80467 BAC80468 BAC80469 EAW99046 Q9NZN1 AB102650 BAC81119 AF181284 AAF59411 AF284435 AAG21369 AJ243874 CAB56046 BC111918 AAI11919 BC126345 AAI26346 BC126347 AAI26348 DN994486 HQ258589 ADR83342 KJ534871 AHW56511 XM_005274441 XP_005274498 XM_011545445 XP_011543747 NM_014271 NP_055086
Function May regulate secretion and presynaptic differentiation through inhibition of the activity of N-type voltage-gated calcium channel. May activate the MAP kinase JNK. Plays a role in presynaptic and postsynaptic differentiation and dendritic spine formation in neurons. {ECO:0000269|PubMed:12783849, ECO:0000269|PubMed:15123616}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:12783849}; Single-pass type I membrane protein {ECO:0000269|PubMed:12783849}. Cytoplasm {ECO:0000269|PubMed:12783849}. Cell projection, axon {ECO:0000250}. Cell projection, dendrite {ECO:0000250}. Note=May localize to the cell body and growth cones of dendrite-like processes. {ECO:0000250}.
Tissue Specificity Detected at low levels in heart, skeletal muscle, ovary, skin, amygdala, caudate nucleus, corpus callosum, hippocampus, substantia nigra and thalamus. Detected at very low levels in tonsil, prostate, testis, small intestine, placenta, colon and fetal liver. {ECO:0000269|PubMed:10471494, ECO:0000269|PubMed:10882729}.

IL-1R8 CRISPR/Cas9 KO Plasmid (h) - sc-410564 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

IL-1R8 HDR Plasmid (h) - sc-410564-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IL-1R8 Double Nickase Plasmid (h) - sc-410564-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IL-1R8 Double Nickase Plasmid (h2) - sc-410564-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IL-1R8 CRISPR Activation Plasmid (h) - sc-410564-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

IL-1R8 CRISPR Activation Plasmid (h2) - sc-410564-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

IL-1R8 Lentiviral Activation Particles (h) - sc-410564-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IL-1R8 Lentiviral Activation Particles (h2) - sc-410564-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IL-1R8 siRNA (h) - sc-91336 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

IL-1R8 shRNA Plasmid (h) - sc-91336-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

IL-1R8 shRNA (h) Lentiviral Particles - sc-91336-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU011961 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN10599 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10599 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

IL1RAPL1 siRNA (Human) - CRH7623 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

IL-1 RAPL1/IL-1 R8 RNAi - H00011141-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

IL1RAPL1 - MBS8237518 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human IL1RAPL1 (NM_014271.3) - SHH318581 from Creative biogene

Category siRNA
Species Reactivities Human

Human IL1RAPL1 siRNA - orb268125 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

IL1RAPL1 shRNA Plasmid (Human) - CHH7623 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

IL1RAPL1 miRNA 3'UTR clone - MiUTR3H-02638 from Creative biogene

Species Reactivities Human
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