PLA2G6

Gene Symbol PLA2G6
Entrez Gene 8398
Alt Symbol CaI-PLA2, GVI, INAD1, IPLA2-VIA, NBIA2, NBIA2A, NBIA2B, PARK14, PLA2, PNPLA9, iPLA2, iPLA2beta
Species Human
Gene Type protein-coding
Description phospholipase A2, group VI (cytosolic, calcium-independent)
Other Description 85 kDa calcium-independent phospholipase A2|85/88 kDa calcium-independent phospholipase A2|GVI PLA2|calcium-independent phospholipase A2|cytosolic, calcium-independent phospholipase A2|group VI phospholipase A2|iPLA2-beta|intracellular membrane-associated calcium-independent phospholipase A2 beta|neurodegeneration with brain iron accumulation 2|patatin-like phospholipase domain containing 9|patatin-like phospholipase domain-containing protein 9
Swissprots O60733 Q9UG29 O75645 A8K597 Q9UIT0 Q9Y671 B0QYE8 Q8N452
Accessions AAD30424 AAF34728 AAR92478 EAW60219 EAW60220 O60733 AF064594 AAC97486 AF102988 AAD41722 AF102989 AAD41723 AK001290 AK096521 BAG53314 AK128862 AK290825 BAF83514 AK291212 BAF83901 AK300459 BAH13289 AK308308 AL080187 CAB45768 BC034592 BC036742 AAH36742 BC051904 AAH51904 CR456543 CAG30429 CU013143 CAK54574 CU013431 CAK54873 XM_005261764 XP_005261821 XM_005261765 XP_005261822 XM_005261766 XP_005261823 XM_005261771 XP_005261828 XM_006724332 XP_006724395 XM_011530422 XP_011528724 XM_011530423 XP_011528725 XM_011530424 XP_011528726 XM_011530425 XP_011528727 XM_011530426 XP_011528728 XM_011530427 XP_011528729 XM_011530428 XP_011528730 XR_244390 XR_244392 XR_430411 XR_430412 XR_937937 XR_937938 XR_937939 XR_937940 NM_001004426 NP_001004426 NM_001199562 NP_001186491 NM_003560 NP_003551
Function Catalyzes the release of fatty acids from phospholipids. It has been implicated in normal phospholipid remodeling, nitric oxide-induced or vasopressin-induced arachidonic acid release and in leukotriene and prostaglandin production. May participate in fas mediated apoptosis and in regulating transmembrane ion flux in glucose-stimulated B-cells. Has a role in cardiolipin (CL) deacylation. Required for both speed and directionality of monocyte MCP1/CCL2-induced chemotaxis through regulation of F- actin polymerization at the pseudopods.
Subcellular Location Isoform LH-iPLA2: Membrane; Peripheral membrane protein. Note=Recruited to the membrane-enriched pseudopod upon MCP1/CCL2 stimulation in monocytes.
Tissue Specificity Four different transcripts were found to be expressed in a distinct tissue distribution.
Top Pathways Fc gamma R-mediated phagocytosis, Vascular smooth muscle contraction, Inflammatory mediator regulation of TRP channels, Ether lipid metabolism, Glycerophospholipid metabolism

Human PLA2G6 / IPLA2 ELISA Kit (Sandwich ELISA) - LS-F5253 from LifeSpan Bioscience

Category ELISA Kit
Prices $650.00
Sizes 1 plate
Sensitivity 31 pg/ml
Range 78.13-5000 pg/ml

Human iPLA2 ELISA Kit - abx152053 from Abbexa

Category ELISA Kit
Sensitivity 32 pg/ml
Range 78.125 pg/ml - 5000 pg/ml

Calcium-independent phospholipase A2, Human, ELISA Kit - E01C2395 from ARP American Research Products

Category ELISA Kit
Prices $535.00, $735.00
Sizes 48 t, 96 t

Phospholipidase A2, Calcium Independent, iPLA2, Human, ELISA Kit - E-EL-H0409 from ARP American Research Products

Category ELISA Kit
Prices $522.00
Sizes 96 t
Sensitivity 0.094
Range 0.156-10ng/mL

Phospholipase A2, Calcium Independent (iPLA2), Human, ELISA Kit - SEA411Hu from ARP American Research Products

Category ELISA Kit
Prices $650.00
Sizes 96 t
Sensitivity 32pg/mL
Range 78-5,000pg/mL

Phospholipase A2, Group IIA (PLA2G2A), Human, ELISA Kit - SED827Hu from ARP American Research Products

Category ELISA Kit
Prices $720.00
Sizes 96 t
Sensitivity 2.55pg/mL
Range 6.25-400pg/mL

Phospholipase A2, Calcium Independent, iPLA2, Mouse, ELISA Kit - E-EL-M1348 from ARP American Research Products

Category ELISA Kit
Prices $585.00
Sizes 96 t
Sensitivity 0.188
Range 0.313-20ng/mL

Phospholipidase A2, Calcium Independent, iPLA2, Rabbit, ELISA Kit - E-EL-RB2187 from ARP American Research Products

Category ELISA Kit
Prices $648.00
Sizes 96 t

Phospholipidase A2, Calcium Independent, iPLA2, Chicken, ELISA Kit - E-EL-Ch0697 from ARP American Research Products

Category ELISA Kit
Prices $504.00
Sizes 96 t

Phospholipidase A2, Calcium Independent, iPLA2, Porcine, ELISA Kit - E-EL-P0262 from ARP American Research Products

Category ELISA Kit
Prices $585.00
Sizes 96 t

Phospholipidase A2, Calcium Independent, iPLA2, Sheep, ELISA Kit - E-EL-S0519 from ARP American Research Products

Category ELISA Kit
Prices $648.00
Sizes 96 t

Phospholipidase A2, Calcium Independent, iPLA2, Guinea Pig, ELISA Kit - E-EL-GP0038 from ARP American Research Products

Category ELISA Kit
Prices $522.00
Sizes 96 t

Phospholipidase A2, Calcium Independent, iPLA2, Monkey, ELISA Kit - E-EL-MK0558 from ARP American Research Products

Category ELISA Kit
Prices $585.00
Sizes 96 t

PLA2G6 (Human) IP-WB Antibody Pair - H00008398-PW1 from Acris Antibodies

Category Antibody Pair
Prices $610.00
Sizes 1 set

ELISA Kit for Phospholipase A2, Calcium Independent (iPLA2) - SEA411Hu from Uscn Life Science Inc.

Category ELISA Kit
Sensitivity The minimum detectable dose of this kit is typically less than 31pg/mL.
Range 78.13-5000pg/mL The standard curve concentrations used for the ELISA’s were 5000pg/mL, 2500pg/mL, 1250pg/mL, 625pg/mL, 312.5pg/mL, 156.25pg/mL, 78.13pg/mL

ELISA Kit for Phospholipase A2, Calcium Independent (iPLA2) - SEA411Ra from Uscn Life Science Inc.

Category ELISA Kit
Sensitivity The minimum detectable dose of this kit is typically less than 0.129ng/mL.
Range 0.313-20ng/mL The standard curve concentrations used for the ELISA’s were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

Human iPLA2(Phospholipase A2, Calcium Independent) ELISA Kit - E-EL-H0409 from Elabscience

Category ELISA Kit
Sensitivity 0.10 ng/mL
Range 0.16—10 ng/mL

Human iPLA2 (Phospholipidase A2, Calcium Independent) CLIA Kit - E-CL-H0330 from Elabscience

Category CLIA Kit
Sensitivity 18.75 pg/mL
Range Average Recovery (%)

Calcium independent phospholipase A2, ELISA Kit - MBS7228069 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Calcium-independent phospholipase A2, ELISA Kit - MBS7223561 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Calcium-independent phospholipase A2, ELISA Kit - MBS7206410 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Calcium-independent phospholipase A2, ELISA Kit - MBS7248163 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Calcium-independent phospholipase A2, ELISA Kit - MBS7224114 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Calcium-independent phospholipase A2, ELISA Kit - MBS7209028 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Calcium-independent phospholipase A2, ELISA Kit - MBS7249507 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
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