| Gene Symbol |
Fdxr
|
| Entrez Gene |
14149
|
| Alt Symbol |
-
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
ferredoxin reductase
|
| Other Description |
AR|NADPH:adrenodoxin oxidoreductase, mitochondrial|adrenodoxin reductase|ferredoxin--NADP(+) reductase
|
| Swissprots |
Q61578
|
| Accessions |
EDL34471 Q61578 AK134068 BAE22000 AK183932 BC057146 AAH57146 BC071268 AAH71268 D49920 BAA08659 XM_006532186 XP_006532249 XR_388346 NM_007997 NP_032023
|
| Function |
Serves as the first electron transfer protein in all the mitochondrial P450 systems. Including cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-beta hydroxylation in the adrenal cortex, 25-OH-vitamin D3-24 hydroxylation in the kidney, and sterol C-27 hydroxylation in the liver.
|
| Subcellular Location |
Mitochondrion matrix.
|
| Tissue Specificity |
Expressed in the adrenal, testis and ovary and to a lesser extent in the liver and kidney.
|