Gene Symbol | Fdxr |
---|---|
Entrez Gene | 14149 |
Alt Symbol | - |
Species | Mouse |
Gene Type | protein-coding |
Description | ferredoxin reductase |
Other Description | AR|NADPH:adrenodoxin oxidoreductase, mitochondrial|adrenodoxin reductase|ferredoxin--NADP(+) reductase |
Swissprots | Q61578 |
Accessions | EDL34471 Q61578 AK134068 BAE22000 AK183932 BC057146 AAH57146 BC071268 AAH71268 D49920 BAA08659 XM_006532186 XP_006532249 XR_388346 NM_007997 NP_032023 |
Function | Serves as the first electron transfer protein in all the mitochondrial P450 systems. Including cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-beta hydroxylation in the adrenal cortex, 25-OH-vitamin D3-24 hydroxylation in the kidney, and sterol C-27 hydroxylation in the liver. |
Subcellular Location | Mitochondrion matrix. |
Tissue Specificity | Expressed in the adrenal, testis and ovary and to a lesser extent in the liver and kidney. |
ADX Reductase CRISPR/Cas9 KO Plasmid (m) - sc-420313 from Santa Cruz Biotechnology
|
||||||||
ADX Reductase HDR Plasmid (m) - sc-420313-HDR from Santa Cruz Biotechnology
|
||||||||
ADX Reductase Double Nickase Plasmid (m) - sc-420313-NIC from Santa Cruz Biotechnology
|
||||||||
ADX Reductase Double Nickase Plasmid (m2) - sc-420313-NIC-2 from Santa Cruz Biotechnology
|
||||||||
ADX Reductase CRISPR Activation Plasmid (m) - sc-420313-ACT from Santa Cruz Biotechnology
|
||||||||
ADX Reductase CRISPR Activation Plasmid (m2) - sc-420313-ACT-2 from Santa Cruz Biotechnology
|
||||||||
ADX Reductase Lentiviral Activation Particles (m) - sc-420313-LAC from Santa Cruz Biotechnology
|
||||||||
ADX Reductase Lentiviral Activation Particles (m2) - sc-420313-LAC-2 from Santa Cruz Biotechnology
|
||||||||
ADX Reductase siRNA (m) - sc-61907 from Santa Cruz Biotechnology
|
||||||||
ADX Reductase shRNA Plasmid (m) - sc-61907-SH from Santa Cruz Biotechnology
|
||||||||
ADX Reductase shRNA (m) Lentiviral Particles - sc-61907-V from Santa Cruz Biotechnology
|
||||||||
MISSION® esiRNA - EMU055431 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN31315 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND31315 from Sigma-Aldrich
|
||||||||
FDXR siRNA (Mouse) - CRM1332 from Cohesion Biosciences
|
||||||||
FDXR - MBS8219501 from MyBioSource
|
||||||||
shRNA set against Mouse FDXR (NM_007997.1) - SHH293981 from Creative biogene
|
||||||||
shRNA set against Mouse Fdxr(NM_007997.1) - SHH055451 from Creative biogene
|
||||||||
Mouse FDXR siRNA - orb280808 from Biorbyt
|
||||||||
FDXR shRNA Plasmid (Mouse) - CHM1332 from Cohesion Biosciences
|
||||||||
FDXR miRNA 3'UTR clone - MiUTR1M-04662 from Creative biogene
|