BAAT

Gene Symbol BAAT
Entrez Gene 570
Alt Symbol BACAT, BAT
Species Human
Gene Type protein-coding
Description bile acid CoA:amino acid N-acyltransferase
Other Description bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase)|bile acid Coenzyme A: amino acid N-acyltransferase (glycine N-choloyltransferase)|bile acid-CoA:amino acid N-acyltransferase|long-chain fatty-acyl-CoA hydrolase
Swissprots Q14032 Q96L31 Q3B7W9
Accessions EAW58943 EAW58944 EAW58945 EAW58946 Q14032 AK315347 BC009567 AAH09567 BC039200 BC107424 AAI07425 BG565737 CB154234 CR541918 CAG46716 DQ891910 ABM82836 DQ895095 ABM86021 H62757 L34081 AAC37550 NM_001127610 NP_001121082 NM_001701 NP_001692
Function Involved in bile acid metabolism. In liver hepatocytes catalyzes the second step in the conjugation of C24 bile acids (choloneates) to glycine and taurine before excretion into bile canaliculi. The major components of bile are cholic acid and chenodeoxycholic acid. In a first step the bile acids are converted to an acyl-CoA thioester, either in peroxisomes (primary bile acids deriving from the cholesterol pathway), or cytoplasmic at the endoplasmic reticulum (secondary bile acids). May catalyze the conjugation of primary or secondary bile acids, or both. The conjugation increases the detergent properties of bile acids in the intestine, which facilitates lipid and fat-soluble vitamin absorption. In turn, bile acids are deconjugated by bacteria in the intestine and are recycled back to the liver for reconjugation (secondary bile acids). May also act as an acyl-CoA thioesterase that regulates intracellular levels of free fatty acids. In vitro, catalyzes the hydrolysis of long- and very lo
Subcellular Location Cytoplasm {ECO:0000269|PubMed:12810727}.
Tissue Specificity Expressed in liver, gallbladder mucosa and pancreas. {ECO:0000269|PubMed:12810727, ECO:0000269|PubMed:2037576}.
Top Pathways Primary bile acid biosynthesis, Peroxisome, Bile secretion, Taurine and hypotaurine metabolism, Biosynthesis of unsaturated fatty acids

BAAT-Over-expression-Lysate - LY12191a from Abgent, a WuXi AppTec company

Category Cell Lysate
Prices $325.00
Sizes 100 µg
Western blot analysis of his-tag BAAT (arrow) using his tag antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the BAAT gene

BAAT overexpression lysate - LY419801 from Acris Antibodies

Category Cell Lysate
Prices $280.00
Sizes 100 µg

BAAT overexpression lysate - LY426822 from Acris Antibodies

Category Cell Lysate
Prices $280.00
Sizes 100 µg

BAAT 293 Cell Lysate - 409276 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

BAAT Overexpression Lysate (Native) - NBL1-07895 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: BAAT Overexpression Lysate (Adult Normal) [NBL1-07895] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for BAAT.

BAAT Over-expression Lysate Product - GWB-3E8587 from Genway Biotech

Category Cell Lysate
Prices $346.00
Sizes 100 µg
Species Human

BAAT Overexpression Lysate (Native) - NBP2-09453 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg

Panoply™ Human BAAT Knockdown Stable Cell Line - CSC-DC001289 from Creative biogene

Category Cell Line
Species Human
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