BAAT

Gene Symbol	BAAT
Entrez Gene	570
Alt Symbol	BACAT, BAT
Species	Human
Gene Type	protein-coding
Description	bile acid CoA:amino acid N-acyltransferase
Other Description	bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase)|bile acid Coenzyme A: amino acid N-acyltransferase (glycine N-choloyltransferase)|bile acid-CoA:amino acid N-acyltransferase|long-chain fatty-acyl-CoA hydrolase
Swissprots	Q14032 Q96L31 Q3B7W9
Accessions	EAW58943 EAW58944 EAW58945 EAW58946 Q14032 AK315347 BC009567 AAH09567 BC039200 BC107424 AAI07425 BG565737 CB154234 CR541918 CAG46716 DQ891910 ABM82836 DQ895095 ABM86021 H62757 L34081 AAC37550 NM_001127610 NP_001121082 NM_001701 NP_001692
Function	Involved in bile acid metabolism. In liver hepatocytes catalyzes the second step in the conjugation of C24 bile acids (choloneates) to glycine and taurine before excretion into bile canaliculi. The major components of bile are cholic acid and chenodeoxycholic acid. In a first step the bile acids are converted to an acyl-CoA thioester, either in peroxisomes (primary bile acids deriving from the cholesterol pathway), or cytoplasmic at the endoplasmic reticulum (secondary bile acids). May catalyze the conjugation of primary or secondary bile acids, or both. The conjugation increases the detergent properties of bile acids in the intestine, which facilitates lipid and fat-soluble vitamin absorption. In turn, bile acids are deconjugated by bacteria in the intestine and are recycled back to the liver for reconjugation (secondary bile acids). May also act as an acyl-CoA thioesterase that regulates intracellular levels of free fatty acids. In vitro, catalyzes the hydrolysis of long- and very lo
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:12810727}.
Tissue Specificity	Expressed in liver, gallbladder mucosa and pancreas. {ECO:0000269|PubMed:12810727, ECO:0000269|PubMed:2037576}.
Top Pathways	Primary bile acid biosynthesis, Peroxisome, Bile secretion, Taurine and hypotaurine metabolism, Biosynthesis of unsaturated fatty acids

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human BAAT protein fragment - ab157951 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

BAAT / BAT Antibody Blocking Peptide - LS-E16681 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human BAAT Protein - H00000570-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

BAAT Blocking Peptide - 33R-4118 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

BAAT - H00000570-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

BAAT - H00000570-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

BAAT fusion protein - Ag8849 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

BAAT fusion protein - Ag8860 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human BAAT, GST-tagged - BAAT-10119H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Bile acid-CoA:amino acid N-acyltransferase(BAAT) - CSB-YP613484HU CSB-EP613484HU CSB-BP613484HU CSB-MP613484HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

BAAT Protein - abx163895 from Abbexa Category Protein Species Human

BAAT (transcript variant 2) - TP325667 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

BAAT Recombinant Protein Antigen - NBP2-14344PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

BAAT-Blocking-Peptide-N-Term - BP22054a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

BAAT-Blocking-Peptide-N-Term - BP22035a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

BAAT Peptide, Human - M34GP01289H from Creative Peptides Category Peptide Source Synthetic. Species Human

Bile acid-CoA:amino acid N-acyltransferase (BAAT), Recombinant Protein - MBS1437262 from MyBioSource Category Protein Prices $1,195.00, $1,195.00, $1,415.00, $1,415.00, $1,920.00, $1,920.00, $2,385.00, $2,385.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Recombinant Human BAAT protein, GST-tagged - BAAT-042H from Creative Biomart Category Protein Source Wheat Germ Species Human

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