| Gene Symbol |
CHRNB2
|
| Entrez Gene |
1141
|
| Alt Symbol |
EFNL3, nAChRB2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
cholinergic receptor, nicotinic, beta 2 (neuronal)
|
| Other Description |
acetylcholine receptor, nicotinic, beta 2 (neuronal)|beta2 human neuronal nicotinic acetylcholine receptor|cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal)|neuronal acetylcholine receptor subunit beta-2|neuronal nicotinic acetylcholine receptor beta 2
|
| Swissprots |
Q9UEH9 P17787
|
| Accessions |
AAD45422 CAA05108 CAD88996 EAW53192 P17787 AK313470 BAG36255 BC075040 AAH75040 BC075041 AAH75041 R40506 U62437 AAB40115 X53179 CAA37320 Y08415 CAA69692 NM_000748 NP_000739
|
| Function |
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane permeable to sodiun ions. {ECO:0000269|PubMed:22361591}.
|
| Subcellular Location |
Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
|
| Top Pathways |
Nicotine addiction, Neuroactive ligand-receptor interaction
|