CYP24A1

Gene Symbol CYP24A1
Entrez Gene 1591
Alt Symbol CP24, CYP24, HCAI, P450-CC24
Species Human
Gene Type protein-coding
Description cytochrome P450, family 24, subfamily A, polypeptide 1
Other Description 1,25-@dihydroxyvitamin D3 24-hydroxylase|1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial|24-OHase|cytochrome P450 24A1|cytochrome P450, subfamily XXIV (vitamin D 24-hydroxylase)|cytochrome P450-CC24|exo-mitochondrial protein|vitamin D 24-hydroxylase|vitamin D(3) 24-hydroxylase
Swissprots Q15807 Q07973 Q5I2W7 Q32ML3
Accessions AAB03776 EAW75573 Q07973 AI400154 AW022349 AY858838 AAW50795 BC109083 AAI09084 BC109084 AAI09085 BI491491 BM928702 BU662901 CN311231 L13286 AAA62379 N29030 S67623 AAB29308 XM_005260304 XP_005260361 NM_000782 NP_000773 NM_001128915 NP_001122387
Function Has a role in maintaining calcium homeostasis. Catalyzes the NADPH-dependent 24-hydroxylation of calcidiol (25- hydroxyvitamin D(3)) and calcitriol (1-alpha,25-dihydroxyvitamin D(3)). The enzyme can perform up to 6 rounds of hydroxylation of calcitriol leading to calcitroic acid. It also shows 23- hydroxylating activity leading to 1-alpha,25-dihydroxyvitamin D(3)-26,23-lactone as end product.
Subcellular Location Mitochondrion.
Top Pathways MicroRNAs in cancer, Steroid biosynthesis

Human CYP24A1 protein fragment - ab152322 from Abcam

Category Protein
Source Wheat germ
Species Human
12.5% SDS-PAGE analysis of ab152322 stained with Coomassie Blue.

CYP24 / CYP24A1 Antibody Blocking Peptide - LS-E27526 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

CYP24 / CYP24A1 Antibody Blocking Peptide - LS-E22025 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

CYP24 / CYP24A1 Antibody Blocking Peptide - LS-E22026 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

CYP24 / CYP24A1 Antibody Blocking Peptide - LS-E9698 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human CYP24A1 Protein - H00001591-Q01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

CYP24A1-Antibody-C-term-Blocking-Peptide - BP8648b from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

CYP24A1 Blocking Peptide - 33R-5247 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

CYP24A1 Blocking Peptide - 33R-7779 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

CYP24A1 Peptide - AC21-2349-P from Abcore

Category Peptide
Prices $160.00
Sizes 100 µg

CYP24A1 - H00001591-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

CYP24A1 - H00001591-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

CYP24A1 Peptide - 42-693P from ProSci

Category Peptide
Species Human, Rat

CYP24A1 fusion protein - Ag17089 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PET28a
Species Human

CYP24A1 fusion protein - Ag16134 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PGEX-4T
Species Human

Recombinant Human CYP24A1, His-tagged - CYP24A1-11768H from Creative Biomart

Category Protein
Source E.coli
Species Human

Recombinant Human CYP24A1, GST-tagged - CYP24A1-120H from Creative Biomart

Category Protein
Source in vitro wheat germ expression system
Species Human

Recombinant Human CYP24A1, GST-tagged - CYP24A1-251H from Creative Biomart

Category Protein
Source Wheat germ
Species Human

Recombinant Cytochrome P450 24A1 (CYP24A1) - RPD543Hu01 from Uscn Life Science Inc.

Category Protein
Source E.coli
Species Human

Recombinant Cytochrome P450 24A1 (CYP24A1) - RPD543Mu01 from Uscn Life Science Inc.

Category Protein
Source E.coli
Species Mouse

CYP24A1 (R439) Peptide - BS2190P from Bioworld Technology

Category Peptide
Prices $158.00
Sizes 100 µl

Recombinant Cytochrome P450 24A1 (CYP24A1) - RPD543Hu01 from Cloud-clone

Category Protein
Source E.coli
Species Human

CYP24A1 Protein - abx164098 from Abbexa

Category Protein
Species Human, Mouse, Rat

Cytochrome P450 24A1 Protein (Recombinant) - abx166986 from Abbexa

Category Protein
Source Human
Species Human

CYP24A1, Peptide - MBS427430 from MyBioSource

Category Peptide
Prices $175.00
Sizes 100 µg
Species Human
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