BMPR1B

Gene Symbol BMPR1B
Entrez Gene 658
Alt Symbol ALK-6, ALK6, CDw293
Species Human
Gene Type protein-coding
Description bone morphogenetic protein receptor, type IB
Other Description BMP type-1B receptor|BMPR-1B|activin receptor-like kinase 6|bone morphogenetic protein receptor type-1B|serine/threonine receptor kinase
Swissprots O00238 B4DSV1 B2R953 P78366
Accessions EAX06060 O00238 AK293008 BAF85697 AK299930 BAG61763 AK313642 BAG36400 AW299723 BC047773 AAH47773 BC069796 AAH69796 BC069803 AAH69803 D89675 BAA19765 U89326 AAC28131 XM_011532201 XP_011530503 XM_011532202 XP_011530504 NM_001203 NP_001194 NM_001256792 NP_001243721 NM_001256793 NP_001243722 NM_001256794 NP_001243723
Function On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP7/OP-1 and GDF5.
Subcellular Location Membrane; Single-pass type I membrane protein.
Top Pathways Cytokine-cytokine receptor interaction, TGF-beta signaling pathway, Hippo signaling pathway, Signaling pathways regulating pluripotency of stem cells

BMPR-IB CRISPR/Cas9 KO Plasmid (h) - sc-417684 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

BMPR-IB HDR Plasmid (h) - sc-417684-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BMPR-IB Double Nickase Plasmid (h) - sc-417684-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BMPR-IB Double Nickase Plasmid (h2) - sc-417684-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BMPR-IB CRISPR Activation Plasmid (h) - sc-417684-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

BMPR-IB CRISPR Activation Plasmid (h2) - sc-417684-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

BMPR-IB Lentiviral Activation Particles (h) - sc-417684-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BMPR-IB Lentiviral Activation Particles (h2) - sc-417684-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BMPR-IB siRNA (h) - sc-40218 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

BMPR-IB shRNA Plasmid (h) - sc-40218-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

BMPR-IB shRNA (h) Lentiviral Particles - sc-40218-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

BMPR-IB/ALK-6 RNAi - H00000658-R01V from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human
Western Blot: BMPR-IB/ALK-6 RNAi [H00000658-R01V] - Analysis of BMPR1B over-expressed 293 cell line. Lane 2 cotransfected with BMPR1B Validated Chimera RNAi Lane 1 non-transfected control. Blot probed with H00000658-M01. GAPDH (36.1 kDa) used as loading control.

MISSION® siRNA - SIHK0173 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

MISSION® siRNA - SIHK0174 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

MISSION® siRNA - SIHK0175 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

CompoZr® Knockout ZFN Kit - CKOZFN1964 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1964 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR01638 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr01638

BMPR1B siRNA (Human) - CRH0453 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

BMPR-IB/ALK-6 RNAi - H00000658-R04 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

BMPR1B - MBS8237908 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

BMPR1B shRNA Plasmid (Human) - CHH0453 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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