| Gene Symbol |
Gad2
|
| Entrez Gene |
14417
|
| Alt Symbol |
6330404F12Rik, GAD(65), GAD65, Gad-2
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
glutamic acid decarboxylase 2
|
| Other Description |
65 kDa glutamic acid decarboxylase|GAD-65|glutamate decarboxylase 2|glutamate decarboxylase 65 kDa isoform
|
| Swissprots |
O35519 P48320
|
| Accessions |
BAB20415 EDL08136 P48320 AF326549 AAL37395 AF326550 AAL37396 AK018118 AK136834 AK141473 BAE24695 AK161857 BC018380 AAH18380 BQ571205 D42051 BAA22893 KC134211 AFX68721 L16980 AAA93049 S67454 AAP14009 XM_011239023 XP_011237325 NM_008078 NP_032104
|
| Function |
Catalyzes the production of GABA.
|
| Subcellular Location |
Cytoplasm, cytosol {ECO:0000250}. Cytoplasmic vesicle {ECO:0000250}. Cell junction, synapse, presynaptic cell membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}. Golgi apparatus membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=Associated to cytoplasmic vesicles. In neurons, cytosolic leaflet of Golgi membranes and presynaptic clusters (By similarity). {ECO:0000250}.
|
| Top Pathways |
Type I diabetes mellitus, GABAergic synapse, Taurine and hypotaurine metabolism, Alanine, aspartate and glutamate metabolism, beta-Alanine metabolism
|