Gene Symbol | Gad2 |
---|---|
Entrez Gene | 14417 |
Alt Symbol | 6330404F12Rik, GAD(65), GAD65, Gad-2 |
Species | Mouse |
Gene Type | protein-coding |
Description | glutamic acid decarboxylase 2 |
Other Description | 65 kDa glutamic acid decarboxylase|GAD-65|glutamate decarboxylase 2|glutamate decarboxylase 65 kDa isoform |
Swissprots | O35519 P48320 |
Accessions | BAB20415 EDL08136 P48320 AF326549 AAL37395 AF326550 AAL37396 AK018118 AK136834 AK141473 BAE24695 AK161857 BC018380 AAH18380 BQ571205 D42051 BAA22893 KC134211 AFX68721 L16980 AAA93049 S67454 AAP14009 XM_011239023 XP_011237325 NM_008078 NP_032104 |
Function | Catalyzes the production of GABA. |
Subcellular Location | Cytoplasm, cytosol {ECO:0000250}. Cytoplasmic vesicle {ECO:0000250}. Cell junction, synapse, presynaptic cell membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}. Golgi apparatus membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=Associated to cytoplasmic vesicles. In neurons, cytosolic leaflet of Golgi membranes and presynaptic clusters (By similarity). {ECO:0000250}. |
Top Pathways | Type I diabetes mellitus, GABAergic synapse, Taurine and hypotaurine metabolism, Alanine, aspartate and glutamate metabolism, beta-Alanine metabolism |
GAD-65 CRISPR/Cas9 KO Plasmid (m) - sc-420471 from Santa Cruz Biotechnology
|
||||||||
GAD-65 HDR Plasmid (m) - sc-420471-HDR from Santa Cruz Biotechnology
|
||||||||
GAD-65 Double Nickase Plasmid (m) - sc-420471-NIC from Santa Cruz Biotechnology
|
||||||||
GAD-65 Double Nickase Plasmid (m2) - sc-420471-NIC-2 from Santa Cruz Biotechnology
|
||||||||
GAD-65 CRISPR Activation Plasmid (m) - sc-420471-ACT from Santa Cruz Biotechnology
|
||||||||
GAD-65 CRISPR Activation Plasmid (m2) - sc-420471-ACT-2 from Santa Cruz Biotechnology
|
||||||||
GAD-65 Lentiviral Activation Particles (m) - sc-420471-LAC from Santa Cruz Biotechnology
|
||||||||
GAD-65 Lentiviral Activation Particles (m2) - sc-420471-LAC-2 from Santa Cruz Biotechnology
|
||||||||
GAD-65 siRNA (m) - sc-41965 from Santa Cruz Biotechnology
|
||||||||
GAD-65 shRNA Plasmid (m) - sc-41965-SH from Santa Cruz Biotechnology
|
||||||||
GAD-65 shRNA (m) Lentiviral Particles - sc-41965-V from Santa Cruz Biotechnology
|
||||||||
MISSION® esiRNA - EMU073031 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN31681 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND31681 from Sigma-Aldrich
|
||||||||
GAD2 siRNA (Mouse) - CRM1478 from Cohesion Biosciences
|
||||||||
GAD2 - MBS8239061 from MyBioSource
|
||||||||
shRNA set against Mouse GAD2 (NM_008078.2) - SHH298681 from Creative biogene
|
||||||||
shRNA set against Mouse Gad2(NM_008078.2) - SHH074909 from Creative biogene
|
||||||||
GAD2 shRNA Plasmid (Mouse) - CHM1478 from Cohesion Biosciences
|
||||||||
GAD2 miRNA 3'UTR clone - MiUTR1M-04897 from Creative biogene
|