CASP7

Gene Symbol	CASP7
Entrez Gene	840
Alt Symbol	CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3
Species	Human
Gene Type	protein-coding
Description	caspase 7, apoptosis-related cysteine peptidase
Other Description	ICE-like apoptotic protease 3|apoptotic protease MCH-3|caspase 7, apoptosis-related cysteine protease|caspase-7
Swissprots	Q5SVL0 Q53YD5 D3DRB8 B4DQU7 Q5SVL3 Q96BA0 B5BU45 P55210 Q13364
Accessions	CAV28504 EAW49494 EAW49495 EAW49496 EAW49497 EAW49498 P55210 AB451281 BAG70095 AB451413 BAG70227 AK223489 AK298964 BAG61059 AK300578 BAG62277 AK301437 BAG62964 AU130224 BC015799 AAH15799 BM976488 BP429646 BQ006259 BQ007179 BT006683 AAP35329 BX487250 BX647973 DC332144 DC364916 DC384804 DQ890614 ABM92231 DQ893769 ABM84695 EU831939 ACE87380 EU832034 ACE86696 U37448 AAC50303 U37449 AAC50304 U39613 AAC50346 U40281 AAC50352 U67206 AAF21460 U67320 AAC51153 XM_006718017 XP_006718080 XM_006718018 XP_006718081 XM_011540259 XP_011538561 XM_011540260 XP_011538562 NM_001227 NP_001218 NM_001267056 NP_001253985 NM_001267057 NP_001253986 NM_001267058 NP_001253987 NM_033338 NP_203124 NM_033339 NP_203125 NM_033340 NP_203126
Function	Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly- 217' bond. Overexpression promotes programmed cell death.
Subcellular Location	Cytoplasm.
Tissue Specificity	Highly expressed in lung, skeletal muscle, liver, kidney, spleen and heart, and moderately in testis. No expression in the brain.
Top Pathways	Apoptosis, Alzheimer's disease, Pertussis, Legionellosis, TNF signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human Caspase-7 full length protein - ab198478 from Abcam Category Protein Prices $1,250.00 Sizes 50 µg Source E. coli Species Human

Caspase-7 peptide - ab39730 from Abcam Category Peptide Prices $176.00 Sizes 50 µg

Human Caspase-7 peptide - ab38267 from Abcam Category Peptide Prices $181.00 Sizes 50 µg Species Human

Human Caspase-7 peptide - ab102735 from Abcam Category Peptide Prices $176.00 Sizes 100 µg Species Human

Human Caspase-7 protein fragment - ab158033 from Abcam Category Protein Prices $402.00 Sizes 2 µg Source Wheat germ Species Human

Human Caspase-7 protein fragment - ab158034 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

CASP7 / Caspase 7 Antibody Blocking Peptide - LS-E30123 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

CASP7 / Caspase 7 Antibody Blocking Peptide - LS-E30122 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

CASP7 / Caspase 7 Antibody Blocking Peptide - LS-E21588 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Caspase-7 Protein - H00000840-Q01 from Novus Biologicals Category Protein Prices $250.00 Sizes 2 µg Source Wheat Germ Species Human

Recombinant Human Caspase-7 Protein - H00000840-Q02 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Caspase-7 Recombinant Protein - P4038 from Novus Biologicals Category Protein Prices $449.00 Sizes 25 units Species Human

Caspase-7 Peptide - NBP1-76608PEP from Novus Biologicals Category Peptide Prices $149.00 Sizes 50 µg Species Human

Caspase-7 Blocking Peptide - NBP1-77210PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

Recombinant Human Caspase-7 Protein - NBP1-99218 from Novus Biologicals Category Protein Prices $195.00 Sizes 25 tests Source E. coli. Species Human

Caspase-7 Protein - NBP1-99590 from Novus Biologicals Category Protein Species Human

Caspase 7 recombinant protein - GTX65039 from GeneTex Category Protein Prices $329.00 Sizes 100 unit Source E. coli Species Human

Caspase 7 recombinant protein - GTX65040 from GeneTex Category Protein Prices $219.00 Sizes 25 unit Source E. coli Species Human

Recombinant Human Caspase-7 - 823-C7-010 from R&D Systems Category Protein Source E. coli-derived, Ala24-Asp198 (p20) & Ala207-Gln303 (p11)

Recombinant Human Caspase-7, CF - 823-C7-010/CF from R&D Systems Category Protein Source E. coli-derived, Ala24-Asp198 (p20) & Ala207-Gln303 (p11)

Recombinant human Caspase-7 protein (OPCA01073) - OPCA01073 from Aviva Systems Biology Category Protein Prices $198.00 Sizes 50 µg Species Human

Recombinant human Caspase-7 protein (OPCA01074) - OPCA01074 from Aviva Systems Biology Category Protein Prices $198.00 Sizes 50 µg Species Human

Human CASP7 protein - orb245623 from Biorbyt Category Protein Prices $315.00, $502.00, $782.00, $1,139.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

Human CASP7 protein - orb245622 from Biorbyt Category Protein Prices $315.00, $502.00, $782.00, $1,139.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

Human CASP7 protein (His Tag) - orb138314 from Biorbyt Category Protein Prices $434.00, $646.00 Sizes 10 μg, 20 μg Source E. coli Species Human

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