CASP7

Gene Symbol CASP7
Entrez Gene 840
Alt Symbol CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3
Species Human
Gene Type protein-coding
Description caspase 7, apoptosis-related cysteine peptidase
Other Description ICE-like apoptotic protease 3|apoptotic protease MCH-3|caspase 7, apoptosis-related cysteine protease|caspase-7
Swissprots Q5SVL0 Q53YD5 D3DRB8 B4DQU7 Q5SVL3 Q96BA0 B5BU45 P55210 Q13364
Accessions CAV28504 EAW49494 EAW49495 EAW49496 EAW49497 EAW49498 P55210 AB451281 BAG70095 AB451413 BAG70227 AK223489 AK298964 BAG61059 AK300578 BAG62277 AK301437 BAG62964 AU130224 BC015799 AAH15799 BM976488 BP429646 BQ006259 BQ007179 BT006683 AAP35329 BX487250 BX647973 DC332144 DC364916 DC384804 DQ890614 ABM92231 DQ893769 ABM84695 EU831939 ACE87380 EU832034 ACE86696 U37448 AAC50303 U37449 AAC50304 U39613 AAC50346 U40281 AAC50352 U67206 AAF21460 U67320 AAC51153 XM_006718017 XP_006718080 XM_006718018 XP_006718081 XM_011540259 XP_011538561 XM_011540260 XP_011538562 NM_001227 NP_001218 NM_001267056 NP_001253985 NM_001267057 NP_001253986 NM_001267058 NP_001253987 NM_033338 NP_203124 NM_033339 NP_203125 NM_033340 NP_203126
Function Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly- 217' bond. Overexpression promotes programmed cell death.
Subcellular Location Cytoplasm.
Tissue Specificity Highly expressed in lung, skeletal muscle, liver, kidney, spleen and heart, and moderately in testis. No expression in the brain.
Top Pathways Apoptosis, Alzheimer's disease, Pertussis, Legionellosis, TNF signaling pathway

caspase-7 CRISPR/Cas9 KO Plasmid (h) - sc-401301 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

caspase-7 HDR Plasmid (h) - sc-401301-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

caspase-7 Double Nickase Plasmid (h) - sc-401301-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

caspase-7 Double Nickase Plasmid (h2) - sc-401301-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

caspase-7 CRISPR Activation Plasmid (h) - sc-401301-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

caspase-7 CRISPR Activation Plasmid (h2) - sc-401301-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

caspase-7 Lentiviral Activation Particles (h) - sc-401301-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

caspase-7 Lentiviral Activation Particles (h2) - sc-401301-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

caspase-7 siRNA (h) - sc-29929 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

caspase-7 shRNA Plasmid (h) - sc-29929-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

caspase-7 shRNA (h) Lentiviral Particles - sc-29929-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU090761 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN1968 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1968 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR09294 from Sigma-Aldrich

Category miRNA

CASP7 siRNA (Human) - CRH0594 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CASP7 - MBS828537 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CASP7 (NM_001227.4) - SHH255013 from Creative biogene

Category siRNA
Species Reactivities Human

Human CASP7 siRNA - orb261096 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CASP7 shRNA Plasmid (Human) - CHH0594 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CASP7 miRNA 3'UTR clone - MiUTR3H-04391 from Creative biogene

Species Reactivities Human

CASP7 miRNA 3'UTR clone - MiUTR3H-04392 from Creative biogene

Species Reactivities Human

CASP7 miRNA 3'UTR clone - MiUTR3H-04393 from Creative biogene

Species Reactivities Human

CASP7 miRNA 3'UTR clone - MiUTR3H-04394 from Creative biogene

Species Reactivities Human
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