Nppb

Gene Symbol Nppb
Entrez Gene 25105
Alt Symbol BNP, Bnf
Species Rat
Gene Type protein-coding
Description natriuretic peptide B
Other Description Brain natriuretic factor|brain natriuretic peptide|gamma-brain natriuretic peptide|iso-ANP|natriuretic peptide precursor B|natriuretic peptide precursor type B|natriuretic peptides B
Swissprots P13205
Accessions AAA21648 AAA41455 AAA41456 EDL81087 P13205 FQ228997 M25297 AAA57269 XM_006239376 XP_006239438 NM_031545 NP_113733
Function Cardiac hormone which may function as a paracrine antifibrotic factor in the heart. Also plays a key role in cardiovascular homeostasis through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3 (By similarity). {ECO:0000250}.
Subcellular Location Secreted.
Tissue Specificity Brain and also in atria, but at much lower levels than ANP.
Top Pathways cGMP-PKG signaling pathway

CompoZr® Knockout ZFN Kit - CKOZFN58113 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND58113 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

NPPB siRNA (Rat) - CRR0443 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Rat

shRNA set against Rat NPPB (NM_031545.1) - SHH354376 from Creative biogene

Category siRNA
Species Reactivities Rat

shRNA set against Rat Nppb(NM_031545.1) - SHG103069 from Creative biogene

Category siRNA
Species Reactivities Rat

Rat NPPB siRNA - orb295292 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Rat

NPPB shRNA Plasmid (Rat) - CHR0443 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Rat

NPPB miRNA 3'UTR clone - MiUTR1R-04257 from Creative biogene

Species Reactivities Rat
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