CHRNA1

Gene Symbol CHRNA1
Entrez Gene 1134
Alt Symbol ACHRA, ACHRD, CHRNA, CMS2A, FCCMS, SCCMS
Species Human
Gene Type protein-coding
Description cholinergic receptor, nicotinic, alpha 1 (muscle)
Other Description acetylcholine receptor subunit alpha|acetylcholine receptor, nicotinic, alpha 1 (muscle)|cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle)|muscle nicotinic acetylcholine receptor|nicotinic acetylcholine receptor alpha subunit|nicotinic cholinergic receptor alpha 1
Swissprots D3DPE8 B4DRV6 P02708
Accessions AAY14687 CAA26344 CAA34960 CAA49705 EAX11124 EAX11125 EAX11126 EAX11127 EAX11128 P02708 AK291338 BAF84027 AK299445 BAG61418 AK315312 BAG37716 BC006314 BC043196 BG828551 CD013889 DQ323657 ABD27888 DQ323658 ABD27889 S77094 AAD14247 Y00762 CAA68731 NM_000079 NP_000070 NM_001039523 NP_001034612
Function After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
Subcellular Location Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Tissue Specificity Isoform 1 is only expressed in skeletal muscle. Isoform 2 is constitutively expressed in skeletal muscle, brain, heart, kidney, liver, lung and thymus.
Top Pathways Neuroactive ligand-receptor interaction

AChRα1 CRISPR/Cas9 KO Plasmid (h) - sc-401880 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

AChRα1 HDR Plasmid (h) - sc-401880-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

AChRα1 Double Nickase Plasmid (h) - sc-401880-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

AChRα1 Double Nickase Plasmid (h2) - sc-401880-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

AChRα1 CRISPR Activation Plasmid (h) - sc-401880-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

AChRα1 CRISPR Activation Plasmid (h2) - sc-401880-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

AChRα1 Lentiviral Activation Particles (h) - sc-401880-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

AChRα1 Lentiviral Activation Particles (h2) - sc-401880-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

AChRα1 siRNA (h) - sc-42524 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

AChRα1 shRNA Plasmid (h) - sc-42524-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

AChRα1 shRNA (h) Lentiviral Particles - sc-42524-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Nicotinic Acetylcholine R alpha 1/CHRNA1 RNAi - H00001134-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU061451 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN1882 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1882 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

CHRNA1 siRNA (Human) - CRH0811 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CHRNA1 - MBS8212073 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CHRNA1 (NM_000079.3) - SHH263513 from Creative biogene

Category siRNA
Species Reactivities Human

CHRNA1 shRNA Plasmid (Human) - CHH0811 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
Search more