POLR2J

Gene Symbol	POLR2J
Entrez Gene	5439
Alt Symbol	POLR2J1, RPB11, RPB11A, RPB11m, hRPB14
Species	Human
Gene Type	protein-coding
Description	polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa
Other Description	DNA-directed RNA polymerase II subunit J-1|DNA-directed RNA polymerase II subunit RPB11-a|RNA polymerase II 13.3 kDa subunit|RNA polymerase II subunit B11-a
Swissprots	O43375 A5D6V8 P52435
Accessions	CAC18368 P52435 AK290515 BAF83204 BC024165 AAH24165 BC040116 BC065711 AAH65711 BC139902 AAI39903 BC141830 AAI41831 BM545237 BM791979 DQ893151 ABM84077 DQ896446 ABM87445 L37127 AAD05361 X82385 CAA57785 X98433 CAA67075 XM_005250452 XP_005250509 NM_006234 NP_006225
Function	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB11 is part of the core element with the central large cleft (By similarity). {ECO:0000250}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:9852112}.
Tissue Specificity	Ubiquitously expressed. High expression was found in heart and skeletal muscle. {ECO:0000269|PubMed:11747469}.
Top Pathways	Huntington's disease, Epstein-Barr virus infection, Purine metabolism, RNA polymerase, Pyrimidine metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human RNA polymerase II RPB11 full length protein - ab134594 from Abcam Category Protein Source E. coli Species Human

POLR2J Antibody Blocking Peptide - LS-E903 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

POLR2J Antibody Blocking Peptide - LS-E3120 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

POLR2J Recombinant Protein - H00005439-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Species Human

Recombinant Human POLR2J Protein - NBP2-23349 from Novus Biologicals Category Protein Prices $269.00 Sizes 50 µg Source E.coli Species Human

POLR2J Protein - NBP2-23347 from Novus Biologicals Category Protein Prices $309.00 Sizes 50 µg Species Human

POLR2J-Antibody-C-Term-Blocking-peptide - BP11300b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

POLR2J-Antibody-C-term-Blocking-Peptide - BP14259b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human POLR2J protein - orb169053 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 2 μg, 10 μg Species Human

POLR2J protein (His tag) - 80R-2526 from Fitzgerald Category Protein Prices $270.00 Sizes 50 µg Source E.coli

POLR2J (1-117, His-tag) - AR50598PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 250 µg Source E. coli Species Human

POLR2J (1-117, His-tag) - AR50598PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 50 µg Source E. coli Species Human

POLR2J - H00005439-P01-02 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Source in vitro transl. Species Human

POLR2J,1-117aa, Human, His tag, E.coli - 01-P1774 from ARP American Research Products Category Protein Prices $149.00, $369.00, $849.00 Sizes 10 µg, 50 µg, 250 µg Species Human

POLR2J fusion protein - Ag9520 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

POLR2J fusion protein - Ag9946 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

POLR2J,1-117aa, Recombinant Protein - GWB-P0264D from Genway Biotech Category Protein Prices $300.00, $900.00 Sizes 50 μg, 250 μg Source E.coli Species Human

Recombinant Human Polymerase (RNA) II (DNA Directed) Polypeptide J, 13.3kDa, His-tagged - POLR2J-7206H from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human POLR2J, GST-tagged - POLR2J-1848H from Creative Biomart Category Protein Source E.coli Species Human

POLR2J1 (D24) Peptide - BS3853P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Human DNA-directed RNA polymerase II subunit RPB11-a(POLR2J) - CSB-YP347112HU CSB-EP347112HU CSB-BP347112HU CSB-MP347112HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

POLR2J,1-117aa, Human, His tag, E.coli - ATGP1774 from ATGen Category Protein Prices $80.00, $240.00, $720.00 Sizes 10 µg, 50 µg, 250 µg Species Human

POLR2J - TP304819 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

POLR2J, Recombinant Protein - MBS204121 from MyBioSource Category Protein Prices $310.00, $720.00 Sizes 50 µg, 250 µg Source E Coli Species Human

Polymerase II, Recombinant Protein - MBS145817 from MyBioSource Category Protein Prices $140.00, $205.00, $5,015.00 Sizes 2 µg, 10 µg, 1 mg Source E Coli

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