POLR2J

Gene Symbol POLR2J
Entrez Gene 5439
Alt Symbol POLR2J1, RPB11, RPB11A, RPB11m, hRPB14
Species Human
Gene Type protein-coding
Description polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa
Other Description DNA-directed RNA polymerase II subunit J-1|DNA-directed RNA polymerase II subunit RPB11-a|RNA polymerase II 13.3 kDa subunit|RNA polymerase II subunit B11-a
Swissprots O43375 A5D6V8 P52435
Accessions CAC18368 P52435 AK290515 BAF83204 BC024165 AAH24165 BC040116 BC065711 AAH65711 BC139902 AAI39903 BC141830 AAI41831 BM545237 BM791979 DQ893151 ABM84077 DQ896446 ABM87445 L37127 AAD05361 X82385 CAA57785 X98433 CAA67075 XM_005250452 XP_005250509 NM_006234 NP_006225
Function DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB11 is part of the core element with the central large cleft (By similarity). {ECO:0000250}.
Subcellular Location Nucleus {ECO:0000269|PubMed:9852112}.
Tissue Specificity Ubiquitously expressed. High expression was found in heart and skeletal muscle. {ECO:0000269|PubMed:11747469}.
Top Pathways Huntington's disease, Epstein-Barr virus infection, Purine metabolism, RNA polymerase, Pyrimidine metabolism

POLR2J1 CRISPR/Cas9 KO Plasmid (h) - sc-409187 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

POLR2J1 HDR Plasmid (h) - sc-409187-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

POLR2J1 Double Nickase Plasmid (h) - sc-409187-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

POLR2J1 Double Nickase Plasmid (h2) - sc-409187-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

POLR2J1 CRISPR Activation Plasmid (h) - sc-409187-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

POLR2J1 CRISPR Activation Plasmid (h2) - sc-409187-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

POLR2J1 Lentiviral Activation Particles (h) - sc-409187-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

POLR2J1 Lentiviral Activation Particles (h2) - sc-409187-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

POLR2J1 siRNA (h) - sc-89724 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

POLR2J1 shRNA Plasmid (h) - sc-89724-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

POLR2J1 shRNA (h) Lentiviral Particles - sc-89724-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

POLR2J RNAi - H00005439-R01 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU117061 from Sigma-Aldrich

Category siRNA

CompoZr® Knockout ZFN Kit - CKOZFN17120 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17120 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

POLR2J siRNA (Human) - CRH3642 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human POLR2J (NM_006234.4) - SHH379484 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human POLR2J(NM_006234.4) - SHR127694 from Creative biogene

Category siRNA
Species Reactivities Human

POLR2J shRNA Plasmid (Human) - CHH3642 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

POLR2J miRNA 3'UTR clone - MiUTR1H-08078 from Creative biogene

Species Reactivities Human
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