ANGPT2

Gene Symbol	ANGPT2
Entrez Gene	607616
Alt Symbol	ANG-2
Species	Dog
Gene Type	protein-coding
Description	angiopoietin 2
Other Description	angiopoietin-2
Swissprots	A0A8J8
Accessions	A0A8J8 AB256019 BAE93229 XM_005629928 XP_005629985 XM_005629929 XP_005629986 NM_001048126 NP_001041591
Function	Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating angiogenic signals mediated by ANGPT1. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal (By similarity). {ECO:0000250}.
Subcellular Location	Secreted {ECO:0000250}.
Top Pathways	PI3K-Akt signaling pathway, Rap1 signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• cDNA Clones
• Cell/Tissue/Blood Products

Canine Angiopoietin-2 / ANG2 Protein (His Tag) - 70034-D07H-10 from Sino Biological Category Protein Source Human Cells Species Dog

Recombinant Dog Angiopoietin-2(ANGPT2) - CSB-YP001707DO CSB-EP001707DO CSB-BP001707DO CSB-MP001707DO from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Dog

Angiopoietin-2(ANGPT2) , Recombinant Protein - MBS965681 from MyBioSource Category Protein Prices $2,060.00, $2,060.00, $2,525.00, $2,525.00 Sizes 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Dog

Canine Angiopoietin-2 / ANG2 Protein (His Tag) - 70034-D07H from ABclonal Category Protein Prices $58.00, $178.00, $448.00 Sizes 10 µg, 50 µg, 200 µg Source Human Cells Species Dog

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