MNAT1

Gene Symbol	MNAT1
Entrez Gene	4331
Alt Symbol	CAP35, MAT1, RNF66, TFB3
Species	Human
Gene Type	protein-coding
Description	MNAT CDK-activating kinase assembly factor 1
Other Description	CDK-activating kinase assembly factor MAT1|CDK7/cyclin-H assembly factor|RING finger protein 66|RING finger protein MAT1|cyclin G1 interacting protein|cyclin-G1-interacting protein|menage a trois 1 (CAK assembly factor)|menage a trois homolog 1, cyclin H assembly factor
Swissprots	Q15817 G3V1U8 Q6ICQ7 P51948
Accessions	AAN47195 EAW80787 EAW80788 EAW80789 EAW80790 EAW80791 P51948 AA053721 AK308701 BC000820 AAH00820 BU620200 CD701743 CR450336 CAG29332 HQ447795 ADQ32279 U61835 AAB05248 X87843 CAA61112 X92669 CAA63356 XM_005267687 XP_005267744 XM_005267688 XP_005267745 XM_011536795 XP_011535097 NM_001177963 NP_001171434 NM_002431 NP_002422
Function	Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. {ECO:0000269|PubMed:10024882}.
Subcellular Location	Nucleus.
Tissue Specificity	Highest levels in colon and testis. Moderate levels are present thymus, prostate, ovary, and small intestine. The lowest levels are found in spleen and leukocytes.
Top Pathways	Nucleotide excision repair, Basal transcription factors

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human MNAT1 full length protein - ab158909 from Abcam Category Protein Source Wheat germ Species Human

Human MNAT1 protein fragment - ab158910 from Abcam Category Protein Source Wheat germ Species Human

MNAT1 Antibody Blocking Peptide - LS-E10952 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MNAT1 Antibody Blocking Peptide - LS-E13698 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human MNAT1 Protein - H00004331-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human MNAT1 Protein - H00004331-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

MNAT1 peptide - orb217624 from Biorbyt Category Peptide Prices $272.00, $510.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat

MNAT1 Blocking Peptide - 33R-5316 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

MNAT1 Blocking Peptide - abx062955 from Abbexa Category Peptide Species Human, Mouse, Rat, Bovine, Pig

MNAT1 / RNF66 - H00004331-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

MNAT1 / RNF66 - H00004331-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

MNAT1 / RNF66 - H00004331-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

MNAT1 / RNF66 - H00004331-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

MNAT1 fusion protein - ag2293 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

MNAT1 Blocking Peptide - CBP1761 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat, Bovine, Pig

MNAT1 (E123) Peptide - BS2011P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Human CDK-activating kinase assembly factor MAT1(MNAT1) - CSB-YP014686HU CSB-EP014686HU CSB-BP014686HU CSB-MP014686HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Human MNAT1 full length protein - ab204195 from Abcam Category Protein Source E. coli Species Human

MNAT1 / RNF66 - TP301595 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

CDK-activating kinase assembly factor MAT1, Recombinant Protein - MBS1010256 from MyBioSource Category Protein Prices $1,085.00, $1,085.00, $1,315.00, $1,315.00, $1,705.00, $1,705.00, $2,170.00, $2,170.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell

CDK-activating kinase assembly factor MAT1 (MNAT1), Recombinant Protein - MBS960505 from MyBioSource Category Protein Prices $1,065.00, $1,065.00, $1,300.00, $1,300.00, $1,670.00, $1,670.00, $2,135.00, $2,135.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

MNAT1 Recombinant Protein Antigen - NBP1-81257PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

MNAT1 Peptide, Human - M34GP09617H from Creative Peptides Category Peptide Source Synthetic. Species Human

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