GOT1

Gene Symbol GOT1
Entrez Gene 100060793
Alt Symbol -
Species Horse
Gene Type protein-coding
Description glutamic-oxaloacetic transaminase 1, soluble
Other Description aspartate aminotransferase cytoplasmic-like protein|glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1)
Swissprots P08906
Accessions HQ889957 AEB61112 XM_001501044 XP_001501094
Function Biosynthesis of L-glutamate from L-aspartate or L- cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3- mercaptopyruvate sulfurtransferase (3MST). Hydrogen sulfide is an important synaptic modulator and neuroprotectant in the brain (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm.
Top Pathways Cysteine and methionine metabolism, Alanine, aspartate and glutamate metabolism, Tyrosine metabolism, Arginine and proline metabolism, Biosynthesis of amino acids

Horse GOT1 ELISA Kit - E074199 from Biobool

Category ELISA Kit
Search more