Gene Symbol | SPARC |
---|---|
Entrez Gene | 386571 |
Alt Symbol | - |
Species | Chicken |
Gene Type | protein-coding |
Description | secreted protein, acidic, cysteine-rich (osteonectin) |
Other Description | BM-40|ON|basement-membrane protein 40|osteonectin|secreted protein acidic and rich in cysteine |
Swissprots | P36377 |
Accessions | P36377 L24906 AAA16893 NM_204410 NP_989741 |
Function | Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity (By similarity). {ECO:0000250}. |
Subcellular Location | Secreted, extracellular space, extracellular matrix, basement membrane {ECO:0000250}. Note=In or around the basement membrane. {ECO:0000250}. |
Tissue Specificity | Detected in aorta, skeletal muscle, calvarium, vertebra, anterior limb, kidney, heart, brain, skin and lung. {ECO:0000269|PubMed:7916692}. |
SPARC (SPARC), Chicken, ELISA Kit - E12S0394 from ARP American Research Products
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SPARC, SPARC, Chicken, ELISA Kit - E0791c from ARP American Research Products
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Chicken ON ELISA Kit - CKO0024 from NeoScientific
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Chicken ON (Osteonectin) ELISA Kit - E-EL-Ch0245 from Elabscience
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Chicken SPARC (Secreted Protein Acidic And Rich In Cysteine) ELISA Kit - E-EL-Ch0975 from Elabscience
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ON, ELISA Kit - MBS2505553 from MyBioSource
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Chicken Osteonectin ELISA - E12O0017 from BlueGene Biotech
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Chicken ON (Osteonectin) ELISA Kit - E-EL-Ch0245 from Iwai North America Inc.
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Chicken SPARC (Secreted Protein Acidic And Rich In Cysteine) ELISA Kit - E-EL-Ch0975 from Iwai North America Inc.
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Chicken SPARC ELISA Kit - E098660 from Biobool
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Chicken ON ELISA Kit - ECKO0024 from ABclonal
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SPARC, ELISA Kit - MBS2881729 from MyBioSource
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