CDYL

Gene Symbol CDYL
Entrez Gene 9425
Alt Symbol CDYL1
Species Human
Gene Type protein-coding
Description chromodomain protein, Y-like
Other Description CDY-like, autosomal|chromodomain Y-like protein|testis-specific chromodomain Y-like protein
Swissprots Q5VX99 Q9Y232 Q9BWZ2 B4DLG4 Q0VDG7 Q32NC5 Q9Y424 Q6P7T5 A8K6D6
Accessions EAW55168 Q9Y232 AF081258 AAD22734 AF081259 AAD22735 AK291601 BAF84290 AK296985 BAG59526 AL050164 CAB43304 BC043397 BC061516 AAH61516 BC108725 AAI08726 BC119682 AAI19683 BE874176 BG766689 BQ930016 BU752976 XM_011514997 XP_011513299 NM_001143970 NP_001137442 NM_001143971 NP_001137443 NM_004824 NP_004815 NR_026590 NM_170752
Function Acts as a RE1-silencing transcription factor (REST) corepressor that facilitates histone-lysine N-methyltransferase EHMT2 recruitment and H3K9 dimethylation at REST target genes for repression. Required for chromatin targeting and maximal enzymatic activity of polycomb repressive complex 2 (PRC2); acts as a positive regulator of PRC2 activity by bridging the pre-existing histone H3K27me3 and newly recruited PRC2 on neighboring nucleosomes. Has histone acetyltransferase activity, with a preference for histone H4. {ECO:0000269|PubMed:12072557, ECO:0000269|PubMed:19061646, ECO:0000269|PubMed:22009739}.
Subcellular Location Nucleus {ECO:0000269|PubMed:18450745, ECO:0000269|PubMed:19808672}.
Tissue Specificity Ubiquitous. Expressed at moderate levels in all tissues examined. Isoform 2 is the most abundantly expressed isoform. {ECO:0000269|PubMed:19808672}.

CDYL (G-15) - sc-34148 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CDYL (G-15): sc-34148. Western blot analysis of CDYL expression in F9 (A), NTERA-2 cl.D1 (B), COLO 320DM (C), AMJ2-C8 (D) whole cell lysates and rat testis tissue extract (E).

CDYL (F-15) - sc-34147 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CDYL (F-15): sc-34147. Immunofluorescence staining of formalin-fixed HeLa cells showing nuclear localization. Kindly provided by Yang Xiang, Ph.D., Division of Newborn Medicine, Boston Childrens Hospital, Cell Biology Department, Harvard Medical School.

CDYL (E-18) - sc-28469 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

CDYL (E-16) - sc-34146 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CDYL (E-16): sc-34146. Western blot analysis of CDYL expression in non-transfected: sc-117752 (A) and human CDYL transfected: sc-112015 (B) 293T whole cell lysates.

Anti-CDYL antibody - ChIP Grade - ab5188 from Abcam

Prices $398.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-CDYL antibody - ChIP Grade (ab5188) at 1/1000 dilutionLane 1 : COS7 (monkey) cellsLane 2 : COS7 cells transfected with HA-CDYL-FLAG plasmid

Anti-CDYL antibody - N-terminal - ab172916 from Abcam

Prices $376.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-CDYL antibody - N-terminal (ab172916) at 1/100 dilution + A375 cell line lysate at 35 µg

Anti-CDYL antibody - ab118362 from Abcam

Prices $376.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Anti-CDYL antibody (ab118362) at 5 µg/ml + Recombinant protein (immunogen) at 0.2 µg

Anti-CDYL antibody - ab3999 from Abcam

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Anti-CDYL antibody (ab3999) at 1 µg/ml + Human Testes lysate (RIPA buffer, 35µg total protein per lane).

Anti-CDYL antibody - ab137423 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-CDYL antibody (ab137423) at 1/1000 dilutionLane 1 : A431 whole cell lysateLane 2 : H1299 whole cell lysateLysates/proteins at 30 µg per lane.

Anti-CDYL Antibody (aa5-34, AP) - LS-C247003 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CDYL Antibody (aa5-34, APC) - LS-C247004 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CDYL Antibody (aa5-34, Biotin) - LS-C247005 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CDYL Antibody (aa5-34, FITC) - LS-C247006 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CDYL Antibody (C-Terminus) - LS-C34652 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
CDYL antibody staining (1 ug/ml) of Human Testes lysate (RIPA buffer, 35g total protein per lane). Primary incubated for 1 hour. Detected by Western blot of chemiluminescence.

Anti-CDYL Antibody (aa51-100) - LS-C111222 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
CDYL antibody LS-C111222 Western blot of Transfected 293T cell lysate.

Anti-CDYL Antibody (aa5-34, PE) - LS-C247007 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CDYL Antibody (aa5-34, Azide-free, HRP) - LS-C249647 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CDYL Antibody (aa153-260) - LS-C306894 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-CDYL Antibody (aa5-34) - LS-C320304 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CDYL Antibody (aa5-34) - LS-C168641 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
CDYL Antibody western blot of A375 cell line lysates (35 ug/lane). The CDYL antibody detected the CDYL protein (arrow).

Anti-CDYL Antibody - LS-C342003 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-CDYL Antibody - LS-C334594 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of U251 cell line, using CDYL antibody.

Anti-CDYL Antibody - LS-C155509 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded BT474 xenograft, using CDYL antibody at 1:250 dilution.

CDYL Antibody - NBP1-52986 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: CDYL Antibody [NBP1-52986] - Transfected 293T cell lysate, concentration 0.2-1 ug/ml.

CDYL Antibody - NBP2-34011 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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