CDYL

Gene Symbol	CDYL
Entrez Gene	9425
Alt Symbol	CDYL1
Species	Human
Gene Type	protein-coding
Description	chromodomain protein, Y-like
Other Description	CDY-like, autosomal|chromodomain Y-like protein|testis-specific chromodomain Y-like protein
Swissprots	Q5VX99 Q9Y232 Q9BWZ2 B4DLG4 Q0VDG7 Q32NC5 Q9Y424 Q6P7T5 A8K6D6
Accessions	EAW55168 Q9Y232 AF081258 AAD22734 AF081259 AAD22735 AK291601 BAF84290 AK296985 BAG59526 AL050164 CAB43304 BC043397 BC061516 AAH61516 BC108725 AAI08726 BC119682 AAI19683 BE874176 BG766689 BQ930016 BU752976 XM_011514997 XP_011513299 NM_001143970 NP_001137442 NM_001143971 NP_001137443 NM_004824 NP_004815 NR_026590 NM_170752
Function	Acts as a RE1-silencing transcription factor (REST) corepressor that facilitates histone-lysine N-methyltransferase EHMT2 recruitment and H3K9 dimethylation at REST target genes for repression. Required for chromatin targeting and maximal enzymatic activity of polycomb repressive complex 2 (PRC2); acts as a positive regulator of PRC2 activity by bridging the pre-existing histone H3K27me3 and newly recruited PRC2 on neighboring nucleosomes. Has histone acetyltransferase activity, with a preference for histone H4. {ECO:0000269|PubMed:12072557, ECO:0000269|PubMed:19061646, ECO:0000269|PubMed:22009739}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:18450745, ECO:0000269|PubMed:19808672}.
Tissue Specificity	Ubiquitous. Expressed at moderate levels in all tissues examined. Isoform 2 is the most abundantly expressed isoform. {ECO:0000269|PubMed:19808672}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

CDYL - MBS1273753 from MyBioSource Species Human Accession BC119682

Human CDYL Gene ORF cDNA clone in cloning vector - HG15826-G from Sino Biological Species Human

Human CDYL Gene ORF cDNA clone expression plasmid, N-HA tag - HG15826-NY from Sino Biological Species Human

Human CDYL Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG15826-ACR from Sino Biological Species Human

Human CDYL Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG15826-ANR from Sino Biological Species Human

Human CDYL Gene ORF cDNA clone expression plasmid, C-His tag - HG15826-CH from Sino Biological Species Human

Human CDYL Gene ORF cDNA clone expression plasmid, N-His tag - HG15826-NH from Sino Biological Species Human

Human CDYL Gene ORF cDNA clone expression plasmid, N-Flag tag - HG15826-NF from Sino Biological Species Human

Human CDYL Gene ORF cDNA clone expression plasmid, C-HA tag - HG15826-CY from Sino Biological Species Human

Human CDYL Gene ORF cDNA clone expression plasmid, C-Flag tag - HG15826-CF from Sino Biological Species Human

Human CDYL Gene ORF cDNA clone expression plasmid - HG15826-UT from Sino Biological Species Human

Human CDYL Gene ORF cDNA clone expression plasmid, C-Myc tag - HG15826-CM from Sino Biological Species Human

Human CDYL Gene ORF cDNA clone expression plasmid, N-Myc tag - HG15826-NM from Sino Biological Species Human

Human CDYL Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG15826-ANG from Sino Biological Species Human

Human CDYL Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG15826-ACG from Sino Biological Species Human

Human CDYL ORF Clone(NM_001143971.1) - CDCR351992 from Creative biogene Species Human

Human CDYL ORF clone (NM_001143970.1) - CDCR045666 from Creative biogene Species Human

Human CDYL ORF Clone (BC119682) - CDCS408374 from Creative biogene Species Human Accession Q9Y232

Human CDYL ORF clone (BC119682) - CDCB157748 from Creative biogene Species Human

Human CDYL cDNA Clone(NM_001143970.1) - CDFH003384 from Creative biogene Species Human

Human CDYL cDNA Clone(NM_001143971.1) - CDFH003385 from Creative biogene Species Human

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