HSP90AA1

Gene Symbol	HSP90AA1
Entrez Gene	3320
Alt Symbol	EL52, HSP86, HSP89A, HSP90A, HSP90N, HSPC1, HSPCA, HSPCAL1, HSPCAL4, HSPN, Hsp89, Hsp90, LAP-2, LAP2
Species	Human
Gene Type	protein-coding
Description	heat shock protein 90kDa alpha (cytosolic), class A member 1
Other Description	HSP 86|LPS-associated protein 2|epididymis luminal secretory protein 52|heat shock 86 kDa|heat shock 90kD protein 1, alpha|heat shock 90kD protein 1, alpha-like 4|heat shock 90kD protein, alpha-like 4|heat shock 90kDa protein 1, alpha|heat shock protein HSP 90-alpha|lipopolysaccharide-associated protein 2|renal carcinoma antigen NY-REN-38
Swissprots	Q5CAQ7 Q5CAQ6 B3KPJ9 A8K500 Q9BVQ5 Q2PP14 P07900
Accessions	AAA36023 AAA63194 ABC40730 EAW81765 EAW81766 EAW81767 EAW81768 P07900 AF028832 AAC25497 AI250920 AJ890082 CAI64495 AJ890083 CAI64496 AK056446 BAG51711 AK129557 AK291115 BAF83804 AK291607 BAF84296 AK300126 BAG61917 AK310595 BC000987 AAH00987 BC001695 BC007989 AAH07989 BC017233 BC023006 AAH23006 BC108695 AAI08696 BC121062 AAI21063 BX247955 CAD62296 BX248761 CAD66568 DA237149 DC303876 GQ149083 ADD71695 X07270 CAA30255 X15183 CAA33259 XM_011536718 XP_011535020 NM_001017963 NP_001017963 NM_005348 NP_005339
Function	Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, including TNF secretion by monocytes. {ECO:0000269|PubMed:11274138, ECO:0000269|PubMed:11276205, ECO:0000269|PubMed:15577939, ECO:0000269|PubMed:15937123}.
Subcellular Location	Cytoplasm. Melanosome. Cell membrane. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Top Pathways	Progesterone-mediated oocyte maturation, Prostate cancer, NOD-like receptor signaling pathway, Protein processing in endoplasmic reticulum, PI3K-Akt signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human Hsp90 alpha full length protein - ab80369 from Abcam Category Protein Prices $302.00 Sizes 100 µg Source E. coli Species Human

Active human Hsp90 alpha full length protein - ab188661 from Abcam Category Protein Prices $527.00 Sizes 50 µg Source E. coli Species Human

Active human Hsp90 alpha protein fragment - ab196407 from Abcam Category Protein Prices $858.00 Sizes 100 µg Source E. coli Species Human

Hsp90 peptide - ab40009 from Abcam Category Peptide Prices $290.00 Sizes 50 µg

Human Hsp90 alpha full length protein - ab85242 from Abcam Category Protein Source Baculovirus infected sf9 cells Species Human

Human Hsp90 alpha full length protein - ab78425 from Abcam Category Protein Source E. coli Species Human

Human Hsp90 alpha full length protein - ab48801 from Abcam Category Protein Source E. coli Species Human

Human Hsp90 alpha protein fragment - ab191657 from Abcam Category Protein Source E. coli Species Human

Human Hsp90 alpha protein fragment - ab191952 from Abcam Category Protein Source E. coli Species Human

Human Hsp90 peptide - ab97362 from Abcam Category Peptide

S. cerevisiae Hsp90 full length protein - ab157271 from Abcam Category Protein Source E. coli Species Yeast

HSP90AA1 / Hsp90 Alpha A1 Antibody Blocking Peptide - LS-E10515 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

HSP90AA1 / Hsp90 Alpha A1 Blocking Peptide - LS-E10792 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

HSP90AA1 / Hsp90 Alpha A1 Antibody Blocking Peptide - LS-E22392 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

HSP90AA1 / Hsp90 Alpha A1 Antibody Blocking Peptide - LS-E22393 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human HSP90 Protein - NBC1-18362 from Novus Biologicals Category Protein Prices $349.00 Sizes 100 µg Source E.coli Species Human

Recombinant Human HSP90 alpha Protein - P3387 from Novus Biologicals Category Protein Prices $549.00 Sizes 100 µg Source E. coli Species Human

HSPCA-Antibody-Center-Blocking-Peptide - BP9085c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

HSPCA-Antibody-C-term-Blocking-Peptide - BP9085b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

HSP90 recombinant protein - GTX65117 from GeneTex Category Protein Prices $319.00 Sizes 25 μg Source Sf9 cells Species Human

Recombinant Human HSP90 alpha, CF - AP-160-050 from R&D Systems Category Protein Source E. coli-derived,

HSP90 Alpha Protein (OPPA01079) - OPPA01079 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 5 µg Source E. Coli

Human Heat Shock Protein 90 Alpha protein - orb81515 from Biorbyt Category Protein Prices $230.00, $442.00 Sizes 5 μg, 20 μg Source E.coli Species Human

Human HSP90AA1 protein - orb245868 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

Human HSP90AA1 protein - orb244280 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

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