ACVR1

Gene Symbol ACVR1
Entrez Gene 90
Alt Symbol ACTRI, ACVR1A, ACVRLK2, ALK2, FOP, SKR1, TSRI
Species Human
Gene Type protein-coding
Description activin A receptor, type I
Other Description TGF-B superfamily receptor type I|activin A receptor, type II-like kinase 2|activin receptor type I|activin receptor type-1|activin receptor-like kinase 2|hydroxyalkyl-protein kinase|serine/threonine-protein kinase receptor R1
Swissprots Q04771
Accessions AAY15094 AAY24272 ADL14509 AJF45349 CAA02405 CAZ91465 CBX47654 EAX11438 EAX11439 EAX11440 EAX11441 EAX11442 EAX11443 Q04771 AK297765 BAG60113 AK313630 BC033867 AAH33867 BC036748 DA796090 L02911 AAA36614 Z22534 CAA80256 XM_005246939 XP_005246996 XM_005246940 XP_005246997 XM_006712825 XP_006712888 XM_011512106 XP_011510408 XM_011512107 XP_011510409 XM_011512108 XP_011510410 NM_001105 NP_001096 NM_001111067 NP_001104537
Function On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin. May be involved for left-right pattern formation during embryogenesis (By similarity). {ECO:0000250}.
Subcellular Location Membrane; Single-pass type I membrane protein.
Tissue Specificity Expressed in normal parenchymal cells, endothelial cells, fibroblasts and tumor-derived epithelial cells.
Top Pathways Cytokine-cytokine receptor interaction, TGF-beta signaling pathway, Signaling pathways regulating pluripotency of stem cells

ACVR1 Antibody - 4398 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from various cell lines using ACVR1 Antibody.

ACTR-I (C-5) - sc-374523 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
ACTR-I (C-5): sc-374523. Western blot analysis of ACTR-I expression in SK-N-SH (A) and ES-2 (B) whole cell lysates.

ACTR-I (E-15) - sc-31294 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

ACTR-I (F-14) - sc-31295 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

ACTR-I (H-170) - sc-25449 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
ACTR-I (H-170): sc-25449. Western blot analysis of ACTR-I expression in SK-N-SH whole cell lysate.

ACTR-I (N-15) - sc-5671 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
ACTR-I (N-15): sc-5671. Western blot analysis of ACTR-I expression in SK-N-SH (A) and ES-2 (B) whole cell lysates.

TGFβ RI (T-19) - sc-402 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
TGFβ RI (T-19): sc-402. Western blot analysis of TGFβ RI expression in SK-N-SH whole cell lysate.

Anti-Activin Receptor Type IA antibody - ab115301 from Abcam

Prices $378.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
ab115301, at 4 µg/ml, staining Activin Receptor Type IA in formalin-fixed, paraffin-embedded Human Testis by Immunohistochemistry, using a biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Anti-Activin Receptor Type IA antibody - ab60157 from Abcam

Prices $379.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
ab60157, at a 1/50-1/100 dilution, staining Activin Receptor Type IA in human hepatocarcinoma on Formalin fixed Paraffin embedded tissue. A peroxidase-conjugated secondary antibody was used, followed by AEC staining.

Anti-Activin Receptor Type IA antibody - ab66924 from Abcam

Prices $376.00
Sizes 200 µl
Host Goat
Clonality Polyclonal
Anti-Activin Receptor Type IA antibody (ab66924) at 0.3 µg/ml + Human Umbilical Cord lysate at 35 µg

Anti-Activin Receptor Type IA antibody - ab60158 from Abcam

Prices $304.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Activin Receptor Type IA antibody (ab60158) at 1/100 dilution + mouse brain lysate

Anti-Activin Receptor Type IA antibody - ab117422 from Abcam

Prices $376.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ab117422, at 5 ug/ml, staining Activin Receptor Type IA in Formalin-fixed, Paraffin-embedded Human adrenal tissue by Immunohistochemistry followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Anti-Activin Receptor Type IA antibody - ab117242 from Abcam

Prices $376.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ab117242, at 10 µg/ml, staining Activin Receptor Type IA in Formalin-fixed, Paraffin-embedded Human Skeletal muscle vessel tissue by Immunohistochemistry followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Anti-Activin Receptor Type IA antibody - ab47086 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Activin Receptor Type IA antibody (ab47086) at 5 µg/ml + mouse kidney lysate

Anti-Activin Receptor Type IA antibody [EPR4076(2)] - ab155981 from Abcam

Prices $378.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR4076(2)
All lanes : Anti-Activin Receptor Type IA antibody [EPR4076(2)] (ab155981) at 1/1000 dilutionLane 1 : Fetal brain lysateLane 2 : Fetal heart lysateLane 3 : Fetal muscle lysateLysates/proteins at 10 µg per lane.SecondaryHRP labeled goat anti-rabbit IgG at 1/2000 dilution

Anti-Activin Receptor Type IA antibody [MM0052-9J17] - ab78414 from Abcam

Prices $376.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone MM0052-9J17
ab78414 at 1/50 dilution, staining Activin Receptor Type IA in human placental tissue section by Immunohistochemistry (Formalin/PFA fixed paraffin-embedded sections).

Anti-Activin Receptor Type IA antibody - N-terminal - ab135633 from Abcam

Prices $376.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-Activin Receptor Type IA antibody - N-terminal (ab135633) at 1/100 dilution + Mouse brain tissue lysate at 12.5 µg

Anti-ALK2 / ACVR1 Antibody (Extracellular Domain) - LS-C122594 from LifeSpan Bioscience

Prices $665.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-ALK2 / ACVR1 Antibody (aa38-87) - LS-C80689 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Transfected 293T cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-ALK2 / ACVR1 Antibody (Extracellular Domain, Biotin) - LS-C124885 from LifeSpan Bioscience

Prices $650.00
Sizes 50 µg
Host Goat
Clonality Polyclonal

Anti-ALK2 / ACVR1 Antibody (aa140-169, AP) - LS-C250752 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ALK2 / ACVR1 Antibody (aa140-169, APC) - LS-C250753 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ALK2 / ACVR1 Antibody (aa140-169, Biotin) - LS-C250754 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ALK2 / ACVR1 Antibody (aa140-169, FITC) - LS-C250755 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ALK2 / ACVR1 Antibody (aa140-169, Azide-free, HRP) - LS-C250756 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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