ACVR1

Gene Symbol ACVR1
Entrez Gene 90
Alt Symbol ACTRI, ACVR1A, ACVRLK2, ALK2, FOP, SKR1, TSRI
Species Human
Gene Type protein-coding
Description activin A receptor, type I
Other Description TGF-B superfamily receptor type I|activin A receptor, type II-like kinase 2|activin receptor type I|activin receptor type-1|activin receptor-like kinase 2|hydroxyalkyl-protein kinase|serine/threonine-protein kinase receptor R1
Swissprots Q04771
Accessions AAY15094 AAY24272 ADL14509 AJF45349 CAA02405 CAZ91465 CBX47654 EAX11438 EAX11439 EAX11440 EAX11441 EAX11442 EAX11443 Q04771 AK297765 BAG60113 AK313630 BC033867 AAH33867 BC036748 DA796090 L02911 AAA36614 Z22534 CAA80256 XM_005246939 XP_005246996 XM_005246940 XP_005246997 XM_006712825 XP_006712888 XM_011512106 XP_011510408 XM_011512107 XP_011510409 XM_011512108 XP_011510410 NM_001105 NP_001096 NM_001111067 NP_001104537
Function On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin. May be involved for left-right pattern formation during embryogenesis (By similarity). {ECO:0000250}.
Subcellular Location Membrane; Single-pass type I membrane protein.
Tissue Specificity Expressed in normal parenchymal cells, endothelial cells, fibroblasts and tumor-derived epithelial cells.
Top Pathways Cytokine-cytokine receptor interaction, TGF-beta signaling pathway, Signaling pathways regulating pluripotency of stem cells

ACTR-I CRISPR/Cas9 KO Plasmid (h) - sc-401283 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ACTR-I HDR Plasmid (h) - sc-401283-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ACTR-I Double Nickase Plasmid (h) - sc-401283-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ACTR-I Double Nickase Plasmid (h2) - sc-401283-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ACTR-I CRISPR Activation Plasmid (h) - sc-401283-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ACTR-I CRISPR Activation Plasmid (h2) - sc-401283-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ACTR-I Lentiviral Activation Particles (h) - sc-401283-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ACTR-I Lentiviral Activation Particles (h2) - sc-401283-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ACTR-I siRNA (h) - sc-40202 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ACTR-I shRNA Plasmid (h) - sc-40202-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ACTR-I shRNA (h) Lentiviral Particles - sc-40202-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Activin RIA/ALK-2/Activin Receptor Type 1 RNAi - H00000090-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU023821 from Sigma-Aldrich

Category siRNA

MISSION® siRNA - SIHK0027 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

MISSION® siRNA - SIHK0026 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

MISSION® siRNA - SIHK0028 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

CompoZr® Knockout ZFN Kit - CKOZFN1906 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1906 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR08189 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr08189

ACVR1 siRNA (Human) - CRH0056 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ACVR1 - MBS8223439 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ACTR-I CRISPR/Cas9 KO Plasmid (h2) - sc-401283-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ACTR-I HDR Plasmid (h2) - sc-401283-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

shRNA set against Human ACVR1 (NM_001105.4) - SHH231214 from Creative biogene

Category siRNA
Species Reactivities Human

ACVR1 shRNA Plasmid (Human) - CHH0056 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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