| Gene Symbol |
Tnfrsf1b
|
| Entrez Gene |
21938
|
| Alt Symbol |
CD120b, TNF-R-II, TNF-R2, TNF-R75, TNF-alphaR2, TNFBR, TNFR80, TNFRII, TNFalpha-R2, Tnfr-1, Tnfr2, p75
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
tumor necrosis factor receptor superfamily, member 1b
|
| Other Description |
TNF receptor beta chain|TNF-RII|TNFR-II|p75 TNFR|p80 TNF-alpha receptor|tumor necrosis factor receptor 2|tumor necrosis factor receptor superfamily member 1B|tumor necrosis factor receptor type II
|
| Swissprots |
P25119 P97893 O88734
|
| Accessions |
AAA85021 CAA60618 CAA74969 EDL29729 EDL29730 P25119 AK004752 BAB23533 AK004844 BAB23610 AK085490 AK140332 BAE24341 AK153301 BAE31883 AK155385 BAE33233 AK156996 AK170464 BC141405 AAI41406 BY489212 M59378 AAA40463 M60469 AAA39752 X76401 CAA53981 NM_011610 NP_035740
|
| Function |
Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2 (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Membrane; Single-pass type I membrane protein.
|
| Top Pathways |
Cytokine-cytokine receptor interaction, Adipocytokine signaling pathway, Amyotrophic lateral sclerosis (ALS), TNF signaling pathway
|