Dnm2

Gene Symbol Dnm2
Entrez Gene 25751
Alt Symbol DYIIAAB
Species Rat
Gene Type protein-coding
Description dynamin 2
Other Description dynamin-2
Swissprots P39052
Accessions EDL78291 EDL78292 EDL78293 EDL78294 P39052 L24562 AAA16746 L25605 AAA19736 XM_006242604 XP_006242666 XM_006242605 XP_006242667 XM_006242608 XP_006242670 XM_006242610 XP_006242672 XM_006242611 XP_006242673 XM_006242612 XP_006242674 XM_006242613 XP_006242675 XM_006242614 XP_006242676 XM_008765917 XP_008764139 XM_008765918 XP_008764140 XM_008765919 XP_008764141 NM_013199 NP_037331
Function Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Plays a role in the regulation of neuron morphology, axon growth and formation of neuronal growth cones (PubMed:21210813). Plays an important role in vesicular trafficking processes, in particular endocytosis (PubMed:19995918). Involved in cytokinesis (PubMed:21195118). {ECO:0000269|PubMed:19995918, ECO:0000269|PubMed:21195118, ECO:0000269|PubMed:21210813}.
Subcellular Location Isoform 4: Cell membrane.
Tissue Specificity Ubiquitously expressed. Brain expression is restricted to glial cells and fibroblasts. Highest levels in the testis. {ECO:0000269|PubMed:9725914}.
Top Pathways Fc gamma R-mediated phagocytosis, Endocytosis, Bacterial invasion of epithelial cells, Endocrine and other factor-regulated calcium reabsorption, Synaptic vesicle cycle

CompoZr® Knockout ZFN Kit - CKOZFN53110 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND53110 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

DNM2 siRNA (Rat) - CRR0932 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Rat

DNM2 - MBS829682 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Rat

shRNA set against Rat DNM2 (NM_013199.1) - SHH279977 from Creative biogene

Category siRNA
Species Reactivities Rat

Rat DNM2 siRNA - orb295781 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Rat

DNM2 shRNA Plasmid (Rat) - CHR0932 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Rat

DNM2 miRNA 3'UTR clone - MiUTR1R-01550 from Creative biogene

Species Reactivities Rat
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