FLOT2

Gene Symbol	FLOT2
Entrez Gene	2319
Alt Symbol	ECS-1, ECS1, ESA, ESA1, M17S1
Species	Human
Gene Type	protein-coding
Description	flotillin 2
Other Description	Flotillin 2 (epidermal surface antigen 1)|epidermal surface antigen|flotillin-2|membrane component chromosome 17 surface marker 1|membrane component, chromosome 17, surface marker 1 (35kD protein identified by monoclonal antibody ECS-1)
Swissprots	Q14254
Accessions	EAW51152 EAW51154 EAW51155 EAW51158 EAW51161 EAW51162 Q14254 AK225491 BC003683 AAH03683 BC017292 AAH17292 BT019477 AAV38284 BT019478 AAV38285 CA390100 CR541784 CAG46583 CR542265 CAG47061 DQ892691 ABM83617 DQ895935 ABM86861 M60922 AAA65729 XM_005257950 XP_005258007 XM_005257952 XP_005258009 XM_005257953 XP_005258010 NM_004475 NP_004466
Function	May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles. May be involved in epidermal cell adhesion and epidermal structure and function.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:20682791}; Peripheral membrane protein {ECO:0000269|PubMed:20682791}. Membrane, caveola {ECO:0000269|PubMed:20682791}; Peripheral membrane protein {ECO:0000269|PubMed:20682791}. Endosome {ECO:0000269|PubMed:20682791}. Note=Membrane-associated protein of caveolae.
Tissue Specificity	In skin, expressed in epidermis and epidermal appendages but not in dermis. Expressed in all layers of the epidermis except the basal layer. In hair follicles, expressed in the suprabasal layer but not the basal layer. Also expressed in melanoma and carcinoma cell lines, fibroblasts and foreskin melanocytes.
Top Pathways	Insulin signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

FLOT2-Over-expression-Lysate - LY12568a from Abgent, a WuXi AppTec company Category Cell Lysate Prices $325.00 Sizes 100 µg

FLOT2 293T Cell Transient Overexpression Lysate(Denatured) - H00002319-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

FLOT2 293T Cell Transient Overexpression Lysate(Denatured) - H00002319-T02 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

FLOT2 293 Cell Lysate - 401297 from ABBIOTEC Category Cell Lysate Prices $672.00 Sizes 100 µg

Flotillin 2 Overexpression Lysate (Denatured) - H00002319-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

Flotillin 2 Overexpression Lysate (Native) - NBL1-10770 from Novus Biologicals Category Cell Lysate Prices $529.00 Sizes 100 µg

Flotillin-2 (h): 293T Lysate - sc-176406 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

FLOT2 Over-expression Lysate Product - GWB-80DE30 from Genway Biotech Category Cell Lysate Prices $756.00 Sizes 100 µg Species Human

Flotillin 2 Overexpression Lysate (Denatured) - H00002319-T02 from Novus Biologicals Category Cell Lysate Prices $299.00 Sizes 100 µl

Search more