FLOT2

Gene Symbol FLOT2
Entrez Gene 2319
Alt Symbol ECS-1, ECS1, ESA, ESA1, M17S1
Species Human
Gene Type protein-coding
Description flotillin 2
Other Description Flotillin 2 (epidermal surface antigen 1)|epidermal surface antigen|flotillin-2|membrane component chromosome 17 surface marker 1|membrane component, chromosome 17, surface marker 1 (35kD protein identified by monoclonal antibody ECS-1)
Swissprots Q14254
Accessions EAW51152 EAW51154 EAW51155 EAW51158 EAW51161 EAW51162 Q14254 AK225491 BC003683 AAH03683 BC017292 AAH17292 BT019477 AAV38284 BT019478 AAV38285 CA390100 CR541784 CAG46583 CR542265 CAG47061 DQ892691 ABM83617 DQ895935 ABM86861 M60922 AAA65729 XM_005257950 XP_005258007 XM_005257952 XP_005258009 XM_005257953 XP_005258010 NM_004475 NP_004466
Function May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles. May be involved in epidermal cell adhesion and epidermal structure and function.
Subcellular Location Cell membrane {ECO:0000269|PubMed:20682791}; Peripheral membrane protein {ECO:0000269|PubMed:20682791}. Membrane, caveola {ECO:0000269|PubMed:20682791}; Peripheral membrane protein {ECO:0000269|PubMed:20682791}. Endosome {ECO:0000269|PubMed:20682791}. Note=Membrane-associated protein of caveolae.
Tissue Specificity In skin, expressed in epidermis and epidermal appendages but not in dermis. Expressed in all layers of the epidermis except the basal layer. In hair follicles, expressed in the suprabasal layer but not the basal layer. Also expressed in melanoma and carcinoma cell lines, fibroblasts and foreskin melanocytes.
Top Pathways Insulin signaling pathway

Flotillin-2 CRISPR/Cas9 KO Plasmid (h) - sc-401200 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Flotillin-2 HDR Plasmid (h) - sc-401200-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Flotillin-2 Double Nickase Plasmid (h) - sc-401200-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Flotillin-2 Double Nickase Plasmid (h2) - sc-401200-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Flotillin-2 CRISPR Activation Plasmid (h) - sc-401200-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Flotillin-2 CRISPR Activation Plasmid (h2) - sc-401200-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Flotillin-2 Lentiviral Activation Particles (h) - sc-401200-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Flotillin-2 Lentiviral Activation Particles (h2) - sc-401200-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Flotillin-2 siRNA (h) - sc-35393 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Flotillin-2 shRNA Plasmid (h) - sc-35393-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Flotillin-2 shRNA (h) Lentiviral Particles - sc-35393-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU008551 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN8826 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8826 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

FLOT2 siRNA (Human) - CRH1624 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

FLOT2 - MBS8226439 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Human FLOT2 siRNA - orb262126 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

FLOT2 shRNA Plasmid (Human) - CHH1624 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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