NFKBIB

Gene Symbol NFKBIB
Entrez Gene 4793
Alt Symbol IKBB, TRIP9
Species Human
Gene Type protein-coding
Description nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
Other Description I-kappa-B-beta|NF-kappa-B inhibitor beta|NF-kappa-BIB|TR-interacting protein 9|TRIP-9|ikB-B|ikB-beta|ikappaBbeta|thyroid receptor-interacting protein 9
Swissprots Q15653 A8K3F4 Q96BJ7
Accessions AAC41742 AAU10088 EAW56839 EAW56840 EAW56841 EAW56842 EAW56843 Q15653 AA044256 AB209784 BAD93021 AB362577 BAF81542 AI684894 AK057862 BAB71599 AK290569 BAF83258 BC007197 AAH07197 BC015528 AAH15528 BI520169 BM008311 BM449613 BQ440907 BT006743 AAP35389 BU150265 BU634404 BX111397 DA633677 DQ890633 ABM92250 DQ893804 ABM84730 XM_006723226 XP_006723289 XM_006723227 XP_006723290 NM_001243116 NP_001230045 NM_002503 NP_002494 NR_040515 NM_001001716
Function Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further NFKBIA- dependent inactivation. Association with inhibitor kappa B- interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.
Subcellular Location Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
Tissue Specificity Expressed in all tissues examined.
Top Pathways Cytosolic DNA-sensing pathway, Influenza A, Herpes simplex infection, Measles, Epstein-Barr virus infection

NFKBIB-Over-expression-Lysate - LY12956a from Abgent, a WuXi AppTec company

Category Cell Lysate
Prices $325.00
Sizes 100 µg
Western blot analysis of his-tag NFKBIB (arrow) using his tag antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the NFKBIB gene

I Kappa B beta (IKBb) - H00004793-T01 from Acris Antibodies

Prices $320.00
Sizes 100 µl

NFKBIB overexpression lysate - LY419285 from Acris Antibodies

Category Cell Lysate
Prices $280.00
Sizes 100 µg

NFKBIB 293 Cell Lysate - 409036 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

IkB-beta Overexpression Lysate (Denatured) - H00004793-T01 from Novus Biologicals

Category Cell Lysate
Prices $299.00
Sizes 100 µl
Species Human
NFKBIB transfected lysate.

IkB-beta Overexpression Lysate (Native) - NBL1-13621 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: IkB beta Overexpression Lysate (Adult Normal) [NBL1-13621] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for IkB beta.

IκB-β (h): 293 Lysate - sc-113183 from Santa Cruz Biotechnology

Category Cell Lysate
Prices $205.00
Sizes 100 µg/200 µl
Species Human

IκB-β (h): 293T Lysate - sc-159317 from Santa Cruz Biotechnology

Category Cell Lysate
Prices $205.00
Sizes 100 µg/200 µl
Species Human

IκB-β (h2): 293T Lysate - sc-159438 from Santa Cruz Biotechnology

Category Cell Lysate
Prices $205.00
Sizes 100 µg/200 µl
Species Human

NFKBIB Over-expression Lysate Product - GWB-C70F59 from Genway Biotech

Category Cell Lysate
Prices $346.00
Sizes 100 µg
Species Human

Panoply™ Human NFKBIB Knockdown Stable Cell Line - CSC-DC010344 from Creative biogene

Category Cell Line
Species Human
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