AKR1C1

Gene Symbol	AKR1C1
Entrez Gene	1645
Alt Symbol	2-ALPHA-HSD, 20-ALPHA-HSD, C9, DD1, DD1/DD2, DDH, DDH1, H-37, HAKRC, HBAB, MBAB
Species	Human
Gene Type	protein-coding
Description	aldo-keto reductase family 1, member C1
Other Description	20 alpha-hydroxysteroid dehydrogenase|20-alpha-hydroxysteroid dehydrogenase|aldo-keto reductase C|aldo-keto reductase family 1 member C1|chlordecone reductase homolog HAKRC|dihydrodiol dehydrogenase 1|dihydrodiol dehydrogenase 1/2|dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase|dihydrodiol dehydrogenase isoform DD1|hepatic dihydrodiol dehydrogenase|high-affinity hepatic bile acid-binding protein|indanol dehydrogenase|trans-1,2-dihydrobenzene-1,2-diol dehydrogenase|type II 3-alpha-hydroxysteroid dehydrogenase
Swissprots	Q9UCX2 P52896 Q5SR15 Q7M4N2 Q04828
Accessions	AAA18115 BAA92886 Q04828 AB031083 BAA92883 AK303435 BAG64483 AK310658 BC015490 AAH15490 BC020216 AAH20216 BC040210 AAH40210 BM923712 BT007197 AAP35861 CB119749 D26124 BAA05121 DQ891484 ABM82410 DQ893923 ABM84849 M86609 AAB02880 S68290 AAD14012 U05684 AAA16227 NM_001353 NP_001344
Function	Converts progesterone to its inactive form, 20-alpha- dihydroxyprogesterone (20-alpha-OHP). In the liver and intestine, may have a role in the transport of bile. May have a role in monitoring the intrahepatic bile acid concentration. Has a low bile-binding ability. May play a role in myelin formation. {ECO:0000269|PubMed:11013348, ECO:0000269|PubMed:8573067}.
Subcellular Location	Cytoplasm.
Tissue Specificity	Expressed in all tissues tested including liver, prostate, testis, adrenal gland, brain, uterus, mammary gland and keratinocytes. Highest levels found in liver, mammary gland and brain. {ECO:0000269|PubMed:11013348}.
Top Pathways	Steroid hormone biosynthesis, Metabolism of xenobiotics by cytochrome P450

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Aldo-keto reductase family 1 member C1 (AKR1C1), Human, ELISA Kit - E01A1371 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Sensitivity 1.0pg/ml Range 100-2500pg/ml

Aldo-keto reductase family 1 member C1, AKR1C1, Human, ELISA Kit - E14181h from ARP American Research Products Category ELISA Kit Prices $736.00 Sizes 96 t Range 0.156-10 ng/mL

AKR1C1 (Human) IP-WB Antibody Pair - H00001645-PW1 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

Aldo keto reductase family 1 member C1 (AKR1C1), ELISA Kit - MBS7219140 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 1.0 pg/mL

Aldo-keto reductase family 1 member C1 (AKR1C1), ELISA Kit - MBS7225931 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Aldo-keto reductase family 1 member C1 (AKR1C1), ELISA Kit - MBS7231825 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Aldo-keto reductase family 1 member C1 (AKR1C1), ELISA Kit - MBS7226235 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Aldo-keto reductase family 1 member C1 (AKR1C1), ELISA Kit - MBS7241367 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Aldo-keto reductase family 1 member C1 (AKR1C1), ELISA Kit - MBS7219869 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Aldo-keto reductase family 1 member C1 (AKR1C1), ELISA Kit - MBS7249325 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Aldo-keto reductase family 1 member C1 (AKR1C1), ELISA Kit - MBS7203510 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Aldo-keto reductase family 1 member C1 (AKR1C1), ELISA Kit - MBS7246529 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Aldo-keto reductase family 1 member C1 (AKR1C1), ELISA Kit - MBS7205841 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Aldo-keto reductase family 1 member C1 (AKR1C1), ELISA Kit - MBS7228889 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Aldo-keto reductase family 1 member C1 (AKR1C1), ELISA Kit - MBS7210995 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1 ng/mL.

aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha) -hydroxysteroid dehydrogenase) , ELISA Kit - MBS9316485 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human Aldo-keto reductase family 1 member C1 ELISA Kit - abx250867 from Abbexa Category ELISA Kit Range 0.156 ng/ml - 10 ng/ml

Human DDH / AKR1C1 ELISA Kit (Sandwich ELISA) - LS-F13056 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.156 Range 0.156-10 ng/ml

Human Aldo-keto reductase family 1 member C1 ELISA Kit - EKE55334 from Biomatik Category ELISA Kit Prices $809.60, $3,440.80, $6,476.80 Sizes 96 t, 5x96t, 10x96t Sensitivity The minimum detectable dose of this kit is typically less than 0.089 ng/ml Range 0.156-10 ng/mL

AKR1C1 - EKH3154 from Nordic BioSite Sensitivity 0.094ng/ml Range 0.156-10ng/ml

AKR1C1 ELISA Kit (Human) : 96 Wells (OKEH02337) - OKEH02337 from Aviva Systems Biology Category ELISA Kit Prices $480.00 Sizes 96 wells Sensitivity < 0.089 ng/mL Range 0.156 - 10 ng/mL

Custom Human AKR1C1 ELISA - ELH-AKR1C1-1 from RayBiotech Category ELISA Kit Prices $627.00, $1,128.60, $2,508.00 Sizes 1 plate kit, 2 plate kit, 5 plate kit

Custom Human AKR1C1 ELISA Kit - orb384463 from Biorbyt Category ELISA Kit Prices $1,411.00, $2,448.00, $5,321.00 Sizes 96 assays, 192 assays, 480 assays

Human AKR1C1 ELISA Kit - E001320 from Biobool Category ELISA Kit Sensitivity 1.0 pg/mL

Human Aldo-keto reductase family 1 member C1 ELISA Kit - EK3357 from Signalway Antibody Category ELISA Kit Prices $739.00 Sizes 1x96t Sensitivity less than 0.089ng/ml Range 0.156-10 ng/mL

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