AKR1C1

Gene Symbol AKR1C1
Entrez Gene 1645
Alt Symbol 2-ALPHA-HSD, 20-ALPHA-HSD, C9, DD1, DD1/DD2, DDH, DDH1, H-37, HAKRC, HBAB, MBAB
Species Human
Gene Type protein-coding
Description aldo-keto reductase family 1, member C1
Other Description 20 alpha-hydroxysteroid dehydrogenase|20-alpha-hydroxysteroid dehydrogenase|aldo-keto reductase C|aldo-keto reductase family 1 member C1|chlordecone reductase homolog HAKRC|dihydrodiol dehydrogenase 1|dihydrodiol dehydrogenase 1/2|dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase|dihydrodiol dehydrogenase isoform DD1|hepatic dihydrodiol dehydrogenase|high-affinity hepatic bile acid-binding protein|indanol dehydrogenase|trans-1,2-dihydrobenzene-1,2-diol dehydrogenase|type II 3-alpha-hydroxysteroid dehydrogenase
Swissprots Q9UCX2 P52896 Q5SR15 Q7M4N2 Q04828
Accessions AAA18115 BAA92886 Q04828 AB031083 BAA92883 AK303435 BAG64483 AK310658 BC015490 AAH15490 BC020216 AAH20216 BC040210 AAH40210 BM923712 BT007197 AAP35861 CB119749 D26124 BAA05121 DQ891484 ABM82410 DQ893923 ABM84849 M86609 AAB02880 S68290 AAD14012 U05684 AAA16227 NM_001353 NP_001344
Function Converts progesterone to its inactive form, 20-alpha- dihydroxyprogesterone (20-alpha-OHP). In the liver and intestine, may have a role in the transport of bile. May have a role in monitoring the intrahepatic bile acid concentration. Has a low bile-binding ability. May play a role in myelin formation. {ECO:0000269|PubMed:11013348, ECO:0000269|PubMed:8573067}.
Subcellular Location Cytoplasm.
Tissue Specificity Expressed in all tissues tested including liver, prostate, testis, adrenal gland, brain, uterus, mammary gland and keratinocytes. Highest levels found in liver, mammary gland and brain. {ECO:0000269|PubMed:11013348}.
Top Pathways Steroid hormone biosynthesis, Metabolism of xenobiotics by cytochrome P450

DD1 CRISPR/Cas9 KO Plasmid (h) - sc-403693 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DD1 HDR Plasmid (h) - sc-403693-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DD1 Double Nickase Plasmid (h) - sc-403693-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DD1 Double Nickase Plasmid (h2) - sc-403693-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DD1 CRISPR Activation Plasmid (h) - sc-403693-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DD1 CRISPR Activation Plasmid (h2) - sc-403693-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DD1 Lentiviral Activation Particles (h) - sc-403693-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DD1 Lentiviral Activation Particles (h2) - sc-403693-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DD1 siRNA (h) - sc-106791 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

DD1 shRNA Plasmid (h) - sc-106791-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

DD1 shRNA (h) Lentiviral Particles - sc-106791-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Aldo-keto Reductase 1C1/AKR1C1 RNAi - H00001645-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN3026 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3026 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR01416 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr01416

AKR1C1 siRNA (Human) - CRH1159 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

AKR1C1 - MBS8216025 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human AKR1C1 (NM_001353.5) - SHH234490 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human AKR1C1(NM_001353.5) - SHG051001 from Creative biogene

Category siRNA
Species Reactivities Human

AKR1C1 shRNA Plasmid (Human) - CHH1159 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

AKR1C1 miRNA 3'UTR clone - MiUTR1H-00275 from Creative biogene

Species Reactivities Human
Search more