CDC5L

Gene Symbol CDC5L
Entrez Gene 988
Alt Symbol CDC5, CDC5-LIKE, CEF1, PCDC5RP, dJ319D22.1
Species Human
Gene Type protein-coding
Description cell division cycle 5-like
Other Description CDC5 cell division cycle 5-like|Cdc5-related protein|cell division cycle 5-like protein|dJ319D22.1 (CDC5-like protein)|pombe cdc5-related protein
Swissprots Q76N46 Q99459 Q99974
Accessions AAR89913 EAX04270 Q99459 AB007892 BAA24862 AK128737 BAG54722 AK299738 BAG61633 BC001568 AAH01568 BG187521 BG497404 BM829346 D85423 BAA20885 DC422730 DQ891623 ABM82549 DQ894814 ABM85740 U86753 AAB61210 XM_006715289 XP_006715352 XR_926346 NM_001253 NP_001244
Function DNA-binding protein involved in cell cycle control. May act as a transcription activator. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR). {ECO:0000269|PubMed:10570151, ECO:0000269|PubMed:11082045, ECO:0000269|PubMed:11101529, ECO:0000269|PubMed:11544257, ECO:0000269|PubMed:12927788, ECO:0000269|PubMed:18583928, ECO:0000269|PubMed:24332808, ECO:0000269|PubMed:9038199, ECO:0000269|PubMed:9468527, ECO:0000269|PubMed:9632794}.
Subcellular Location Nucleus {ECO:0000269|PubMed:10570151, ECO:0000269|PubMed:11544257, ECO:0000269|PubMed:18583928, ECO:0000269|PubMed:9038199, ECO:0000269|PubMed:9598309}. Nucleus speckle {ECO:0000269|PubMed:10570151, ECO:0000269|PubMed:10827081, ECO:0000269|PubMed:11544257}. Cytoplasm {ECO:0000269|PubMed:9038199}. Note=May shuttle between cytoplasm and nucleus. {ECO:0000269|PubMed:9038199}.
Tissue Specificity Ubiquitously expressed in both fetal and adult tissues. {ECO:0000269|PubMed:9038199, ECO:0000269|PubMed:9598309, ECO:0000269|PubMed:9632794}.
Top Pathways Spliceosome

CDC5L 293 Cell Lysate - 409386 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

CDC5L Overexpression Lysate (Native) - NBL1-09013 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: CDC5L Overexpression Lysate (Adult Normal) [NBL1-09013] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for CDC5L.

Cdc5L (h2): 293T Lysate - sc-173633 from Santa Cruz Biotechnology

Category Cell Lysate
Prices $205.00
Sizes 100 µg/200 µl
Species Human

CDC5L Over-expression Lysate Product - GWB-14B70D from Genway Biotech

Category Cell Lysate
Prices $445.00
Sizes 100 µg
Species Human

Panoply™ Human CDC5L Knockdown Stable Cell Line - CSC-DC002817 from Creative biogene

Category Cell Line
Species Human
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