APOC1

Gene Symbol APOC1
Entrez Gene 341
Alt Symbol Apo-CI, ApoC-I
Species Human
Gene Type protein-coding
Description apolipoprotein C-I
Other Description apo-CIB|apoC-IB|apolipoprotein C-I variant I|apolipoprotein C1
Swissprots Q6IB97 B2R526 P02654
Accessions AAA51763 AAA88018 AAD02506 AAQ91813 ACN81312 EAW57307 EAW57308 P02654 AF308154 AAG49499 AF308155 AAG49500 AI310334 AI885116 AK225971 AK312036 BAG34973 AM392727 CAL37605 BC009698 AAH09698 BC055093 AAH55093 BT007142 AAP35806 CR456907 CAG33188 GQ129384 ACT64518 GQ129385 ACT64519 M27359 AAA51762 X00570 CAA25235 XM_005258855 XP_005258912 NM_001645 NP_001636
Function Inhibitor of lipoprotein binding to the low density lipoprotein (LDL) receptor, LDL receptor-related protein, and very low density lipoprotein (VLDL) receptor. Associates with high density lipoproteins (HDL) and the triacylglycerol-rich lipoproteins in the plasma and makes up about 10% of the protein of the VLDL and 2% of that of HDL. Appears to interfere directly with fatty acid uptake and is also the major plasma inhibitor of cholesteryl ester transfer protein (CETP). Binds free fatty acids and reduces their intracellular esterification. Modulates the interaction of APOE with beta-migrating VLDL and inhibits binding of beta-VLDL to the LDL receptor-related protein. {ECO:0000269|PubMed:17339654, ECO:0000303|PubMed:25160599}.
Subcellular Location Secreted {ECO:0000303|PubMed:2835369}.
Tissue Specificity Synthesized mainly in liver and to a minor degree in intestine. Also found in the lung and spleen. {ECO:0000269|PubMed:2835369}.

apoC-I (E-12) - sc-162533 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
apoC-I (E-12): sc-162533. Immunofluorescence staining of formalin-fixed Hep G2 cells showing cytoplasmic localization.

apoC-I (T-13) - sc-162535 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

apoC-I (Y-13) - sc-101263 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
apoC-I (Y-13): sc-101263 Western blot analysis of apoC-I expression in human apoC-I transfected (A) and non-transfected (B) 293T whole cell lysates.

Anti-Apolipoprotein CI antibody - ab189866 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-Apolipoprotein CI antibody (ab189866) at 1/500 dilution + Apolipoprotein CI recombinant protein

Anti-Apolipoprotein CI antibody - ab85870 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC image of Apolipoprotein CI staining in Human normal liver formalin fixed paraffin embedded tissue section, performed on a Leica Bond™ system using the standard protocol F. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab85870, 5µg/ml, for 15 mins at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. For other IHC staining systems (automated and non-automated) customers should optimize variable parameters such as antigen retrieval conditions, primary antibody concentration and antibody incubation times.

Anti-Apolipoprotein CI antibody [EPR16813] - ab198288 from Abcam

Prices $347.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR16813
Anti-Apolipoprotein CI antibody [EPR16813] (ab198288) at 1/1000 dilution + Human fetal liver lysate at 20 µgSecondaryAnti-Rabbit IgG (HRP), specific to the non-reduced form of IgG at 1/1000 dilution

Anti-Apolipoprotein CI antibody - C-terminal - ab188644 from Abcam

Prices $407.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human liver tissue labeling Apolipoprotein CI with ab188644 at 3.75 µg/ml followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Anti-Apolipoprotein CI antibody - ab20793 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ICC/IF image of ab20793 stained HeLa cells. The cells were 4% formaldehyde fixed (10 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab20793, 5µg/ml) overnight at +4°C. The secondary antibody (green) was ab96899, DyLight® 488 goat anti-rabbit IgG (H+L) used at a 1/250 dilution for 1h.Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM.

Anti-Apolipoprotein CI antibody - ab104446 from Abcam

Prices $407.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
ab104446, at 5 ug/ml, staining Apolipoprotein CI in formalin-fixed, paraffin-embedded Human Liver by Immunohistochemistry, using a biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Anti-Apolipoprotein CI antibody - ab20051 from Abcam

Prices $370.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-Apolipoprotein CI antibody - ab54800 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Anti-Apolipoprotein CI antibody (ab54800) at 5 µg/ml + 0.2 µg/lane of full length recombinant protein with a tagSecondaryGoat anti mouse IgG (H&L)-HRP conjugate at 1/5000 dilution

Anti-Apolipoprotein CI antibody - ab7617 from Abcam

Prices $370.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-Apolipoprotein CI antibody - ab37721 from Abcam

Prices $406.00
Sizes 50 µg
Host Chicken
Clonality Polyclonal
Serum protein as test antigen. ab37721 as primary antibody and Goat anti-IgY-HRP as 2nd antibody. Fixed amount of Antibody (5µg/ml) and serial dilutions of antigen.

Anti-Apolipoprotein CI antibody - ab106822 from Abcam

Prices $370.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Staining of paraffin embedded Human Liver tissue with ab106822 at 3.8µg/ml. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

Anti-Apolipoprotein CI antibody (Biotin) - ab27634 from Abcam

Prices $370.00
Sizes 100 µl
Host Goat
Clonality Polyclonal

Anti-Apolipoprotein CI antibody (FITC) - ab27645 from Abcam

Prices $370.00
Sizes 100 µl
Host Goat
Clonality Polyclonal

Anti-Apolipoprotein CI antibody (HRP) - ab21185 from Abcam

Prices $370.00
Sizes 250 µl
Host Goat
Clonality Polyclonal

Anti-APOC1 / Apolipoprotein C I Antibody - LS-C20735 from LifeSpan Bioscience

Prices $515.00
Sizes 1 mg
Host Goat
Clonality Polyclonal

Anti-APOC1 / Apolipoprotein C I Antibody - LS-C47245 from LifeSpan Bioscience

Prices $275.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-APOC1 / Apolipoprotein C I Antibody - LS-C47246 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-Apolipoprotein C-I / APOC1 Antibody - LS-C69174 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-Apolipoprotein C-I / APOC1 Antibody - LS-C69175 from LifeSpan Bioscience

Host Goat
Clonality Polyclonal

Anti-APOC1 / Apolipoprotein C I Antibody - LS-C60058 from LifeSpan Bioscience

Prices $395.00
Sizes 1 mg
Host Goat
Clonality Polyclonal

Anti-APOC1 / Apolipoprotein C I Antibody - LS-C69176 from LifeSpan Bioscience

Prices $485.00
Sizes 200 µg
Host Goat
Clonality Polyclonal

Anti-APOC1 / Apolipoprotein C I Antibody - LS-C126853 from LifeSpan Bioscience

Prices $365.00
Sizes 1 ml
Host Goat
Clonality Polyclonal
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