APOC1

Gene Symbol APOC1
Entrez Gene 341
Alt Symbol Apo-CI, ApoC-I
Species Human
Gene Type protein-coding
Description apolipoprotein C-I
Other Description apo-CIB|apoC-IB|apolipoprotein C-I variant I|apolipoprotein C1
Swissprots Q6IB97 B2R526 P02654
Accessions AAA51763 AAA88018 AAD02506 AAQ91813 ACN81312 EAW57307 EAW57308 P02654 AF308154 AAG49499 AF308155 AAG49500 AI310334 AI885116 AK225971 AK312036 BAG34973 AM392727 CAL37605 BC009698 AAH09698 BC055093 AAH55093 BT007142 AAP35806 CR456907 CAG33188 GQ129384 ACT64518 GQ129385 ACT64519 M27359 AAA51762 X00570 CAA25235 XM_005258855 XP_005258912 NM_001645 NP_001636
Function Inhibitor of lipoprotein binding to the low density lipoprotein (LDL) receptor, LDL receptor-related protein, and very low density lipoprotein (VLDL) receptor. Associates with high density lipoproteins (HDL) and the triacylglycerol-rich lipoproteins in the plasma and makes up about 10% of the protein of the VLDL and 2% of that of HDL. Appears to interfere directly with fatty acid uptake and is also the major plasma inhibitor of cholesteryl ester transfer protein (CETP). Binds free fatty acids and reduces their intracellular esterification. Modulates the interaction of APOE with beta-migrating VLDL and inhibits binding of beta-VLDL to the LDL receptor-related protein. {ECO:0000269|PubMed:17339654, ECO:0000303|PubMed:25160599}.
Subcellular Location Secreted {ECO:0000303|PubMed:2835369}.
Tissue Specificity Synthesized mainly in liver and to a minor degree in intestine. Also found in the lung and spleen. {ECO:0000269|PubMed:2835369}.

apoC1 CRISPR/Cas9 KO Plasmid (h) - sc-403713 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

apoC1 HDR Plasmid (h) - sc-403713-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

apoC1 Double Nickase Plasmid (h) - sc-403713-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

apoC1 Double Nickase Plasmid (h2) - sc-403713-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

apoC1 CRISPR Activation Plasmid (h) - sc-403713-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

apoC1 CRISPR Activation Plasmid (h2) - sc-403713-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

apoC1 Lentiviral Activation Particles (h) - sc-403713-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

apoC1 Lentiviral Activation Particles (h2) - sc-403713-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

apoC-I siRNA (h) - sc-97370 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

apoC-I shRNA Plasmid (h) - sc-97370-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

apoC-I shRNA (h) Lentiviral Particles - sc-97370-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU125971 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN3342 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3342 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

APOC1 siRNA (Human) - CRH0240 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Apolipoprotein C1 RNAi - H00000341-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

APOC1 - MBS8223584 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human APOC1 (NM_001645.3) - SHH238482 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human APOC1(NM_001645.3) - SHG065521 from Creative biogene

Category siRNA
Species Reactivities Human

Human APOC1 siRNA - orb260742 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

APOC1 shRNA Plasmid (Human) - CHH0240 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

APOC1 miRNA 3'UTR clone - MiUTR1H-00477 from Creative biogene

Species Reactivities Human
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