UBB
| Gene Symbol | UBB |
|---|---|
| Entrez Gene | 7314 |
| Alt Symbol | - |
| Species | Human |
| Gene Type | protein-coding |
| Description | ubiquitin B |
| Other Description | polyubiquitin B|polyubiquitin-B |
| Swissprots | P0CG47 |
| Accessions | BAC56955 CAA28495 CAV30745 EAX04501 EAX04502 EAX04503 EAX04504 EAX04505 EAX04506 P0CG47 AA659395 AK129498 AK300882 BAG62524 BC000379 AAH00379 BC009301 AAH09301 BC015127 AAH15127 BC026301 AAH26301 BC031027 AAH31027 BC038999 AAH38999 BC046123 AAH46123 BG548604 BG718912 BM554254 BM662083 BP307496 BT020104 AAV38907 BU596366 BU661443 DB480830 HY014043 NM_001281716 NP_001268645 NM_001281717 NP_001268646 NM_001281718 NP_001268647 NM_001281719 NP_001268648 NM_001281720 NP_001268649 NM_018955 NP_061828 |
| Function | Ubiquitin: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair; Lys-11-linked is involved in ERAD (endoplasmic reticulum-associated degradation) and in cell-cycle regulation; Lys-29-linked is involved in lysosomal degradation; Lys-33-linked is involved in kinase modification; Lys-48-linked is involved in protein degradation via the proteasome; Lys-63-linked is involved in endocytosis, DNA-damage responses as well as in signaling processes leading to activation of the transcription fac |
| Subcellular Location | Ubiquitin: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. |
UBB - MBS1274182 from MyBioSource
|
||||
UBB - MBS1272020 from MyBioSource
|
||||
Human UBB cDNA clone(NM_018955.2) - CDFG002123 from Creative Biomart
|
||||
Human UBB cDNA clone(NM_018955.2) - CDFG002124 from Creative Biomart
|
||||
Human UBB ORF Clone(NM_018955.2) - CDCR304324 from Creative Biomart
|
||||
Human UBB ORF Clone(NM_018955.2) - CDCR304325 from Creative Biomart
|
||||
Human UBB ORF Clone(NM_018955.2) - CDCR304324 from Creative biogene
|
||||
Human UBB ORF Clone (BC000379) - CDCS414889 from Creative biogene
|
||||
Human UBB ORF Clone (BC009301) - CDCS414890 from Creative biogene
|
||||
Human UBB ORF Clone (BC014880) - CDCS419902 from Creative biogene
|
||||
Human UBB cDNA Clone(NM_018955.2) - CDFG002123 from Creative biogene
|
||||
Human UBB cDNA Clone(NM_018955.2) - CDFG002124 from Creative biogene
|
||||
Human UBB Gene ORF cDNA clone expression plasmid, N-HA tag - HG16831-NY from Sino Biological
|
||||
Human UBB Gene ORF cDNA clone in cloning vector - HG16831-U from Sino Biological
|