UBB

Gene Symbol	UBB
Entrez Gene	7314
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	ubiquitin B
Other Description	polyubiquitin B|polyubiquitin-B
Swissprots	P0CG47
Accessions	BAC56955 CAA28495 CAV30745 EAX04501 EAX04502 EAX04503 EAX04504 EAX04505 EAX04506 P0CG47 AA659395 AK129498 AK300882 BAG62524 BC000379 AAH00379 BC009301 AAH09301 BC015127 AAH15127 BC026301 AAH26301 BC031027 AAH31027 BC038999 AAH38999 BC046123 AAH46123 BG548604 BG718912 BM554254 BM662083 BP307496 BT020104 AAV38907 BU596366 BU661443 DB480830 HY014043 NM_001281716 NP_001268645 NM_001281717 NP_001268646 NM_001281718 NP_001268647 NM_001281719 NP_001268648 NM_001281720 NP_001268649 NM_018955 NP_061828
Function	Ubiquitin: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair; Lys-11-linked is involved in ERAD (endoplasmic reticulum-associated degradation) and in cell-cycle regulation; Lys-29-linked is involved in lysosomal degradation; Lys-33-linked is involved in kinase modification; Lys-48-linked is involved in protein degradation via the proteasome; Lys-63-linked is involved in endocytosis, DNA-damage responses as well as in signaling processes leading to activation of the transcription fac
Subcellular Location	Ubiquitin: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human Penta-ubiquitin full length protein - ab189669 from Abcam Category Protein Prices $408.00 Sizes 25 µg Source E. coli Species Human

Active human Poly-ubiquitin (linkage-specific K48) full length protein - ab189706 from Abcam Category Protein Prices $452.00 Sizes 100 µg Source E. coli Species Human

Active human Tetra-ubiquitin (linkage-specific K48) full length protein - ab189689 from Abcam Category Protein Prices $342.00 Sizes 25 µg Source E. coli Species Human

Active human Tetra-ubiquitin (linkage-specific K63) (biotinylated ) full length protein - ab189683 from Abcam Category Protein Prices $454.00 Sizes 25 µg Source E. coli Species Human

Active human Ubiquitin (methyl ) full length protein - ab189710 from Abcam Category Protein Prices $408.00 Sizes 100 µg Source E. coli Species Human

Active human Ubiquitin full length protein - ab189223 from Abcam Category Protein Prices $572.00 Sizes 50 µg Source E. coli Species Human

Active human Ubiquitin full length protein - ab189663 from Abcam Category Protein Prices $232.00 Sizes 100 µg Source E. coli Species Human

Active human Ubiquitin full length protein - ab189751 from Abcam Category Protein Prices $452.00 Sizes 50 µg Source E. coli Species Human

Active human Ubiquitin K48 only protein full length protein - ab157048 from Abcam Category Protein Prices $302.00 Sizes 25 µg Source E. coli Species Human

Active human Ubiquitin K48 only protein full length protein - ab189672 from Abcam Category Protein Prices $454.00 Sizes 50 µg Source E. coli Species Human

Active human Ubiquitin protein fragment - ab157043 from Abcam Category Protein Prices $302.00 Sizes 25 µg Source E. coli Species Human

Active human Ubiquitin protein fragment - ab189229 from Abcam Category Protein Prices $461.00 Sizes 50 µg Source E. coli Species Human

Di-ubiquitin (linkage-specific K48) protein - ab189659 from Abcam Category Protein Prices $298.00 Sizes 100 µg Source E. coli Species Human

Human Di-ubiquitin (linkage-specific K11) full length protein - ab180031 from Abcam Category Protein Source E. coli Species Human

Human Di-ubiquitin (linkage-specific K11) full length protein - ab189680 from Abcam Category Protein Source E. coli Species Human

Human Di-ubiquitin (linkage-specific K11) full length protein - ab189703 from Abcam Category Protein Source E. coli Species Human

Human Di-ubiquitin (linkage-specific K27) full length protein - ab178484 from Abcam Category Protein Source Synthetic Species Human

Human Di-ubiquitin (linkage-specific K29) full length protein - ab178485 from Abcam Category Protein Source Synthetic Species Human

Human Di-ubiquitin (linkage-specific K33) full length protein - ab178487 from Abcam Category Protein Source Synthetic Species Human

Human Di-ubiquitin (linkage-specific K48) full length protein - ab139766 from Abcam Category Protein Source Synthetic Species Human

Human Di-ubiquitin (linkage-specific K48) full length protein - ab189753 from Abcam Category Protein Source E. coli Species Human

Human Di-ubiquitin (linkage-specific K6) full length protein - ab178486 from Abcam Category Protein Source Synthetic Species Human

Human Di-ubiquitin (linkage-specific K63) full length protein - ab179856 from Abcam Category Protein Source E. coli Species Human

Human Di-ubiquitin (linkage-specific K63) full length protein - ab189237 from Abcam Category Protein Source E. coli Species Human

Human Di-ubiquitin (linkage-specific K63) full length protein - ab189725 from Abcam Category Protein Source E. coli Species Human

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