CDC6

Gene Symbol CDC6
Entrez Gene 990
Alt Symbol CDC18L, HsCDC18, HsCDC6
Species Human
Gene Type protein-coding
Description cell division cycle 6
Other Description CDC6 cell division cycle 6 homolog|CDC6-related protein|cdc18-related protein|cell division control protein 6 homolog|cell division cycle 6 homolog|p62(cdc6)
Swissprots Q8TB30 Q99741
Accessions AAN10296 CAG24445 EAW60650 EAW60651 Q99741 AA210818 AF022109 AAC52071 AK313620 BAG36382 BC025232 AAH25232 BE296640 BE548194 BF203219 DQ892840 ABM83766 DQ896087 ABM87086 U77949 AAB38317 XM_011525541 XP_011523843 XM_011525542 XP_011523844 NM_001254 NP_001245
Function Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated.
Subcellular Location Nucleus {ECO:0000269|PubMed:9566895}. Cytoplasm {ECO:0000269|PubMed:9566895}. Note=The protein is nuclear in G1 and cytoplasmic in S-phase cells.
Top Pathways Cell cycle

Cdc6 (C42F7) Rabbit mAb - 3387 from Cell Signaling Technology

Prices $99.00, $246.00
Sizes 20 µl (2 western blots), 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone C42F7
Western blot analysis of extracts from various cell types using Cdc6 (C42F7) Rabbit mAb.

Cdc6 (D-1) - sc-13136 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Cdc6 (D-1): sc-13136. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic localization.

Cdc6 (DCS-180) - sc-56273 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Cdc6 (DCS-180): sc-56273. Western blot analysis of Cdc6 expression in HeLa whole cell lysate.

Cdc6 (C-20) - sc-32507 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Cdc6 (H-304) - sc-8341 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Cdc6 (H-304): sc-8341. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human breast tumor showing cytoplasmic and nuclear staining.

Cdc6 (180.2) - sc-9964 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Cdc6 (180.2): sc-9964. Immunoperoxidase staining of formalin fixed, paraffin-embedded human breast tumor (A) and immunofluorescence staining of methanol-fixed HeLa cells (B) showing cytoplasmic staining.

Cdc6 (0.T.17) - sc-70826 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Cdc6 (0.T.17): sc-70826. Western blot analysis of Cdc6 expression in non-transfected: sc-117752 (A) and human Cdc6 transfected: sc-173781 (B) 293T whole cell lysates.

Cdc6 (0.N.189) - sc-70827 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Cdc6 (0.N.189): sc-70827. Western blot analysis of Cdc6 expression in non-transfected: sc-117752 (A) and human Cdc6 transfected: sc-173781 (B) 293T whole cell lysates.

p-Cdc6 (Ser 106) - sc-12922 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
p-Cdc6 (Ser 106)-R: sc-12922-R. Western blot analysis of Cdc6 phosphorylation in serum starved then serum treated (A) and serum starved then serum and lambda protein phosphatase treated (B) HeLa whole cell lysates.

p-Cdc6 (Ser 54) - sc-12920 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Western blot analysis of Cdc6 phosphorylation in untreated (A, C), and lambda protein phosphatase treated (B, D) HeLa whole cell lysates. Antibodies tested include p-Cdc6 (Ser 54)-R: sc-12920-R (A, C) and Cdc6 (D-1): sc-13136 (B, D).

p-Cdc6 (Ser 74) - sc-12921 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-Cdc6 (phospho S106) antibody [EPR761(2)] - ab76422 from Abcam

Prices $313.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR761(2)
All lanes : Anti-Cdc6 (phospho S106) antibody [EPR761(2)] (ab76422) at 1/2000 dilutionLane 1 : Raji cell lysateLane 2 : Raji cell lysate treated with FBSLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/1000 dilution

Anti-Cdc6 (phospho S54) antibody - ab53689 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Cdc6 (phospho S54) antibody (ab53689) at 1/500 dilutionLane 1 : COS7 cell extract treated with EGF (200ng/ml, 30 mins)Lane 2 : COS7 cell extract treated with EGF (200ng/ml, 30 mins) with immunising peptide

Anti-Cdc6 (phospho S54) antibody [EPR759Y] - ab75809 from Abcam

Prices $313.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR759Y
All lanes : Anti-Cdc6 (phospho S54) antibody [EPR759Y] (ab75809) at 1/2000 dilutionLane 1 : Raji cell lysateLane 2 : Raji + FBS cell lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-Cdc6 antibody - ab155759 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-Cdc6 antibody (ab155759) at 1/1000 dilution + Jurkat whole cell lysate at 30 µg

Anti-Cdc6 antibody - ab53696 from Abcam

Prices $378.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Cdc6 antibody (ab53696) at 1/500 dilutionLane 1 : HT29 cell extractLane 2 : HT29 cell extract with the immunising peptide

Anti-Cdc6 antibody - ab188634 from Abcam

Prices $376.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human testis tissue labeling Cdc6 with ab186348 at 10 µg/ml.

Anti-Cdc6 antibody - ab125195 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ab125195 at 1/100 dilution staining Cdc6 in Formalin-Fixed, Paraffin-Embedded Human colon carcinoma tissue by Immunohistochemistry. Detection: DAB staining.

Anti-Cdc6 antibody - ab64880 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Cdc6 antibody (ab64880) at 1/500 dilutionLane 1 : extracts from K562 cells, (5-30µg total protein).Lane 2 : extracts from K562 cells, (5-30µg total protein) and 5-10µg of the immunising peptide.

Anti-Cdc6 antibody - ab173266 from Abcam

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Anti-Cdc6 antibody (ab173266) at 0.00999999977648 µg/ml + Nuclear Jurkat lysate (in RIPA buffer) at 35 µgdeveloped using the ECL technique

Anti-Cdc6 antibody - ab174630 from Abcam

Prices $376.00
Sizes 200 µl
Host Goat
Clonality Polyclonal
Anti-Cdc6 antibody (ab174630) at 0.00999999977648 µg + Jurkat cell lysate at 35 µg

Anti-Cdc6 antibody [DCS-180] - ab140244 from Abcam

Prices $376.00
Sizes 500 µl
Host Mouse
Clonality Monoclonal
Clone DCS-180
Immunoprecipitation of native Cdc6 from MDA231 cells by ab140244.

Anti-Cdc6 antibody [DCS-180] - ab3220 from Abcam

Prices $373.00
Sizes 500 µl
Host Mouse
Clonality Monoclonal
Clone DCS-180

Anti-Cdc6 antibody [EPR714(2)] - ab109315 from Abcam

Prices $387.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR714(2)
All lanes : Anti-Cdc6 antibody [EPR714(2)] (ab109315) at 1/10000 dilutionLane 1 : Hela treated with hydroxyurea lysateLane 2 : Raji treated with FBS lysatesLysates/proteins at 10 µg per lane.

Anti-Cdc6 antibody - N-terminal - ab188423 from Abcam

Prices $384.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-Cdc6 antibody - N-terminal (ab188423) at 1/1000 dilution + HeLa cell lysate at 10 µg
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