XYLT2

Gene Symbol XYLT2
Entrez Gene 64132
Alt Symbol PXYLT2, XT-II, XT2, xylT-II
Species Human
Gene Type protein-coding
Description xylosyltransferase II
Other Description UDP-D-xylose:proteoglycan core protein beta-D-xylosyltransferase|peptide O-xylosyltransferase 1|protein xylosyltransferase 2|xylosyltransferase 2
Swissprots Q9H1B5 Q6UY41 Q86V00
Accessions EAW94626 EAW94627 Q9H1B5 AJ277442 CAC16788 AK299999 BAG61818 AL833210 AY358090 AAQ88457 BC017084 BC036069 BC052262 AAH52262 BC156444 AAI56445 BM726479 BQ018370 XM_005257572 XP_005257629 XM_011525114 XP_011523416 NM_022167 NP_071450 NR_110010
Function Probably catalyzes the first step in biosynthesis of glycosaminoglycan. Transfers D-xylose from UDP-D-xylose to specific serine residues of the core protein. Initial enzyme in the biosynthesis of chondroitin sulfate and dermatan sulfate proteoglycans in fibroblasts and chondrocytes (By similarity). Its enzyme activity has not been demonstrated. {ECO:0000250}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
Tissue Specificity Widely expressed. Expressed at higher level in kidney and pancreas. {ECO:0000269|PubMed:11099377}.
Top Pathways Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate, Glycosaminoglycan biosynthesis - heparan sulfate / heparin

XYLT2 - MBS1275697 from MyBioSource

Species Human
Accession BC052262

Human XYLT2 ORF Clone(NM_022167.2) - CDCL181465 from Creative Biomart

Species Human
Accession NM_022167.2

Human XYLT2 ORF Clone(NM_022167.2) - CDCR307401 from Creative Biomart

Species Human
Accession NM_022167.2

Human XYLT2 ORF Clone(NM_022167.2) - CDCR307402 from Creative Biomart

Species Human
Accession NM_022167.2

Human XYLT2 ORF Clone(NM_022167.2) - CDCR307403 from Creative Biomart

Species Human
Accession NM_022167.2

Human XYLT2 ORF Clone(NM_022167.2) - CDCR307401 from Creative biogene

Species Human

Human XYLT2 ORF Clone (BC052262) - CDCS419961 from Creative biogene

Species Human
Accession Q9H1B5
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