XYLT2

Gene Symbol XYLT2
Entrez Gene 64132
Alt Symbol PXYLT2, XT-II, XT2, xylT-II
Species Human
Gene Type protein-coding
Description xylosyltransferase II
Other Description UDP-D-xylose:proteoglycan core protein beta-D-xylosyltransferase|peptide O-xylosyltransferase 1|protein xylosyltransferase 2|xylosyltransferase 2
Swissprots Q9H1B5 Q6UY41 Q86V00
Accessions EAW94626 EAW94627 Q9H1B5 AJ277442 CAC16788 AK299999 BAG61818 AL833210 AY358090 AAQ88457 BC017084 BC036069 BC052262 AAH52262 BC156444 AAI56445 BM726479 BQ018370 XM_005257572 XP_005257629 XM_011525114 XP_011523416 NM_022167 NP_071450 NR_110010
Function Probably catalyzes the first step in biosynthesis of glycosaminoglycan. Transfers D-xylose from UDP-D-xylose to specific serine residues of the core protein. Initial enzyme in the biosynthesis of chondroitin sulfate and dermatan sulfate proteoglycans in fibroblasts and chondrocytes (By similarity). Its enzyme activity has not been demonstrated. {ECO:0000250}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
Tissue Specificity Widely expressed. Expressed at higher level in kidney and pancreas. {ECO:0000269|PubMed:11099377}.
Top Pathways Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate, Glycosaminoglycan biosynthesis - heparan sulfate / heparin

XylT-II CRISPR/Cas9 KO Plasmid (h) - sc-404853 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

XylT-II HDR Plasmid (h) - sc-404853-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

XylT-II Double Nickase Plasmid (h) - sc-404853-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

XylT-II Double Nickase Plasmid (h2) - sc-404853-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

XylT-II CRISPR Activation Plasmid (h) - sc-404853-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

XylT-II CRISPR Activation Plasmid (h2) - sc-404853-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

XylT-II Lentiviral Activation Particles (h) - sc-404853-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

XylT-II Lentiviral Activation Particles (h2) - sc-404853-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

XylT-II siRNA (h) - sc-61819 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

XylT-II shRNA Plasmid (h) - sc-61819-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

XylT-II shRNA (h) Lentiviral Particles - sc-61819-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU014561 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN22993 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22993 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR06796 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr06796

XYLT2 siRNA (Human) - CRJ1940 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

XYLT2 - MBS8225726 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human XYLT2 (NM_022167.2) - SHH448216 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human XYLT2(NM_022167.2) - SHL139390 from Creative biogene

Category siRNA
Species Reactivities Human

Human XYLT2 siRNA - orb272441 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

XYLT2 shRNA Plasmid (Human) - CHJ1940 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

XYLT2 miRNA 3'UTR clone - MiUTR1H-11329 from Creative biogene

Species Reactivities Human
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