| Gene Symbol | Opn4 |
|---|---|
| Entrez Gene | 192223 |
| Alt Symbol | - |
| Species | Rat |
| Gene Type | protein-coding |
| Description | opsin 4 |
| Other Description | melanopsin|opn4 {ECO:0000312|RGD:621701}|opsin-4 |
| Swissprots | Q8R456 |
| Accessions | EDL88866 EDL88867 Q8R456 AY072689 AAL61854 NM_138860 NP_620215 |
| Function | Photoreceptor required for regulation of circadian rhythm. Contributes to pupillar reflex and other non-image forming responses to light. May be able to isomerize covalently bound all- trans retinal back to 11-cis retinal. {ECO:0000269|PubMed:11834834}. |
| Subcellular Location | Cell membrane {ECO:0000269|PubMed:11834834}; Multi-pass membrane protein {ECO:0000269|PubMed:11834834}. Note=Found in soma, dendrites and proximal part of axons of certain retinal ganglion cells. |
| Tissue Specificity | Eye; expressed in a photosensitive subset of retinal ganglion cells. {ECO:0000269|PubMed:11834834}. |
Recombinant Rat OPN4 Protein - OPN4-4192R from Creative Biomart
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Melanopsin (Opn4), Recombinant Protein - MBS7024572 from MyBioSource
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