Gene Symbol | Opn4 |
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Entrez Gene | 192223 |
Alt Symbol | - |
Species | Rat |
Gene Type | protein-coding |
Description | opsin 4 |
Other Description | melanopsin|opn4 {ECO:0000312|RGD:621701}|opsin-4 |
Swissprots | Q8R456 |
Accessions | EDL88866 EDL88867 Q8R456 AY072689 AAL61854 NM_138860 NP_620215 |
Function | Photoreceptor required for regulation of circadian rhythm. Contributes to pupillar reflex and other non-image forming responses to light. May be able to isomerize covalently bound all- trans retinal back to 11-cis retinal. {ECO:0000269|PubMed:11834834}. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:11834834}; Multi-pass membrane protein {ECO:0000269|PubMed:11834834}. Note=Found in soma, dendrites and proximal part of axons of certain retinal ganglion cells. |
Tissue Specificity | Eye; expressed in a photosensitive subset of retinal ganglion cells. {ECO:0000269|PubMed:11834834}. |
CompoZr® Knockout ZFN Kit - CKOZFN59564 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND59564 from Sigma-Aldrich
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OPN4 siRNA (Rat) - CRR3498 from Cohesion Biosciences
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shRNA set against Rat OPN4 (NM_138860.1) - SHH366692 from Creative biogene
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shRNA set against Rat Opn4(NM_138860.1) - SHR071318 from Creative biogene
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OPN4 shRNA Plasmid (Rat) - CHR3498 from Cohesion Biosciences
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OPN4 miRNA 3'UTR clone - MiUTR1R-05543 from Creative biogene
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