SLC29A1

Gene Symbol SLC29A1
Entrez Gene 2030
Alt Symbol ENT1
Species Human
Gene Type protein-coding
Description solute carrier family 29 (equilibrative nucleoside transporter), member 1
Other Description equilibrative NBMPR-sensitive nucleoside transporter|equilibrative nitrobenzylmercaptopurine riboside (NBMPR)-sensitive nucleoside transporter|equilibrative nitrobenzylmercaptopurine riboside-sensitive nucleoside transporter|equilibrative nucleoside transporter 1|nucleoside transporter, es-type|solute carrier family 29 (nucleoside transporters), member 1|solute carrier family 29 member 1|solute carrier family 29, member 1
Swissprots Q9UJY2 Q5T9W9 B3KQY5 B3KQV7 Q99808
Accessions AAF02777 AAM11785 EAX04254 EAX04255 EAX04256 Q99808 AB490708 BAI39492 AB490709 BAI39493 AF079117 AAC62495 AK090491 BAG52169 AK090615 BAG52197 AK293558 BAH11534 AK304285 BAH14150 AX775997 CAE11698 BC001382 AAH01382 BC008954 AAH08954 BC095398 BM661584 CB996332 DA559201 DA680982 DC396448 DQ892133 ABM83059 DQ895327 ABM86253 U81375 AAC51103 XM_005248876 XP_005248933 XM_005248878 XP_005248935 XM_005248879 XP_005248936 XM_005248880 XP_005248937 XM_005248881 XP_005248938 XM_005248882 XP_005248939 XM_011514341 XP_011512643 NM_001078177 NP_001071645 NM_001304462 NP_001291391 NM_001304463 NP_001291392 NM_001304465 NP_001291394 NM_001304466 NP_001291395 NM_001078174 NM_001078176 NM_004955 NM_001078175 NP_001071643
Function Mediates both influx and efflux of nucleosides across the membrane (equilibrative transporter). It is sensitive (ES) to low concentrations of the inhibitor nitrobenzylmercaptopurine riboside (NBMPR) and is sodium-independent. It has a higher affinity for adenosine. Inhibited by dipyridamole and dilazep (anticancer chemotherapeutics drugs).
Subcellular Location Basolateral cell membrane; Multi-pass membrane protein. Apical cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Note=Predominantly localized in the basolateral membrane in polarized MDCK cells.
Tissue Specificity Detected in erythrocytes (at protein level). Expressed in heart, brain, mammary gland, erythrocytes and placenta, and also in fetal liver and spleen. {ECO:0000269|PubMed:12527552, ECO:0000269|PubMed:23219802}.
Top Pathways Alcoholism

ENT1 (F-12) - sc-377283 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
ENT1 (F-12): sc-377283. Western blot analysis of ENT1 expression in mouse heart (A) and rat heart (B) tissue extracts.

ENT1 (M-130) - sc-134502 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
ENT1 (M-130): sc-134502. Western blot analysis of ENT1 expression in mouse heart tissue extract.

ENT1 (H-115) - sc-134501 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
ENT1 (H-115): sc-134501. Immunoperoxidase staining of formalin fixed, paraffin-embedded human fallopian tube tissue showing cytoplasmic staining of glandular cells.

ENT1 (N-12) - sc-48489 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
ENT1 (N-12): sc-48489. Western blot analysis of ENT1 expression in rat heart tissue extract.

Anti-ENT1 antibody - ab135756 from Abcam

Prices $384.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-ENT1 antibody (ab135756) at 1/1000 dilutionLane 1 : Human Kidney LysateLane 2 : Human Plasma LysateLane 3 : Mouse Kidney LysateLane 4 : Mouse Plasma LysateLane 5 : Rat Kidney LysateLysates/proteins at 35 µg per lane.SecondaryGoat anti-rabbit IgG H+L conjugated HRP at 1/5000 dilution

Anti-ENT1 antibody - ab48607 from Abcam

Prices $382.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-ENT1 antibody (ab48607) at 2 µg/mlLane 1 : Heart (Human) Tissue Lysate - adult normal tissue (ab29431)Lane 2 : Brain (Human) Tissue Lysate - adult normal tissue (ab29466)Lane 3 : Heart (Human) Tissue Lysate - adult normal tissue (ab29431) with Human ENT1 peptide (ab48606) at 2 µg/mlLane 4 : Brain (Human) Tissue Lysate - adult normal tissue (ab29466) with Human ENT1 peptide (ab48606) at 2 µg/mlLysates/proteins at 10 µg per lane.SecondaryGoat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilutionPerformed under reducing conditions.

Anti-ENT1 antibody - ab150493 from Abcam

Prices $376.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human placenta tissue labelling ENT1 with ab150493 at 2.5 µg/ml.

Anti-ENT1 antibody - ab135391 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-ENT1 antibody (ab135391) at 1/500 dilution + MDA MB 435 cell extracts at 30 µg

Anti-ENT1 antibody [SP120] - ab182023 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone SP120
Immunohistochemical analysis of formalin-fixed paraffin-embedded Human pancreas tissue labeling ENT1 with ab182023.

Anti-ENT1 antibody - N-terminal - ab190877 from Abcam

Prices $376.00
Sizes 200 µl
Host Goat
Clonality Polyclonal
Anti-ENT1 antibody - N-terminal (ab190877) at 1 µg/ml + Human placenta lysate (in RIPA buffer) at 35 µgdeveloped using the ECL technique

Anti-SLC29A1 / ENT1 Antibody (aa402-431) - LS-C96639 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical of paraffin-embedded R. brain section using ENT1(Slc29a1). Antibody was diluted at 1:25 dilution. A peroxidase-conjugated goat anti-rabbit IgG at 1:400 dilution was used as the secondary antibody, followed by DAB staining.

Anti-SLC29A1 / ENT1 Antibody (aa234-263) IHC-plus™ - LS-B3385 from LifeSpan Bioscience

Prices $395.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
Anti-ENT1 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3385 concentration 10 ug/ml.

Anti-SLC29A1 / ENT1 Antibody (aa15-64) - LS-C199845 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts from MDA-MB-435 cells, using ENT1 antibody.

Anti-SLC29A1 / ENT1 Antibody (Internal, AP) - LS-C218982 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC29A1 / ENT1 Antibody (Ser254) IHC-plus™ - LS-B8989 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Testis, Human: Formalin-Fixed, Paraffin-Embedded (FFPE)

Anti-SLC29A1 / ENT1 Antibody (Internal, APC) - LS-C218983 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC29A1 / ENT1 Antibody (Internal, Biotin) - LS-C218984 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC29A1 / ENT1 Antibody (phospho-Ser254) - LS-C97135 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Dot blot of anti-Phospho-ENT1(Slc29a1)-pS254 Antibody on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5ug per ml.

Anti-SLC29A1 / ENT1 Antibody (Internal, FITC) - LS-C218986 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC29A1 / ENT1 Antibody (N-Terminus) - LS-C178673 from LifeSpan Bioscience

Prices $255.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SLC29A1 / ENT1 Antibody (Internal, Azide-free, HRP) - LS-C218987 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC29A1 / ENT1 Antibody (C-Terminus, AP) - LS-C218988 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC29A1 / ENT1 Antibody (C-Terminus, APC) - LS-C218989 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC29A1 / ENT1 Antibody (Internal, PE) - LS-C218990 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC29A1 / ENT1 Antibody (Ser254, AP) - LS-C218991 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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