SLC29A1

Gene Symbol SLC29A1
Entrez Gene 2030
Alt Symbol ENT1
Species Human
Gene Type protein-coding
Description solute carrier family 29 (equilibrative nucleoside transporter), member 1
Other Description equilibrative NBMPR-sensitive nucleoside transporter|equilibrative nitrobenzylmercaptopurine riboside (NBMPR)-sensitive nucleoside transporter|equilibrative nitrobenzylmercaptopurine riboside-sensitive nucleoside transporter|equilibrative nucleoside transporter 1|nucleoside transporter, es-type|solute carrier family 29 (nucleoside transporters), member 1|solute carrier family 29 member 1|solute carrier family 29, member 1
Swissprots Q9UJY2 Q5T9W9 B3KQY5 B3KQV7 Q99808
Accessions AAF02777 AAM11785 EAX04254 EAX04255 EAX04256 Q99808 AB490708 BAI39492 AB490709 BAI39493 AF079117 AAC62495 AK090491 BAG52169 AK090615 BAG52197 AK293558 BAH11534 AK304285 BAH14150 AX775997 CAE11698 BC001382 AAH01382 BC008954 AAH08954 BC095398 BM661584 CB996332 DA559201 DA680982 DC396448 DQ892133 ABM83059 DQ895327 ABM86253 U81375 AAC51103 XM_005248876 XP_005248933 XM_005248878 XP_005248935 XM_005248879 XP_005248936 XM_005248880 XP_005248937 XM_005248881 XP_005248938 XM_005248882 XP_005248939 XM_011514341 XP_011512643 NM_001078177 NP_001071645 NM_001304462 NP_001291391 NM_001304463 NP_001291392 NM_001304465 NP_001291394 NM_001304466 NP_001291395 NM_001078174 NM_001078176 NM_004955 NM_001078175 NP_001071643
Function Mediates both influx and efflux of nucleosides across the membrane (equilibrative transporter). It is sensitive (ES) to low concentrations of the inhibitor nitrobenzylmercaptopurine riboside (NBMPR) and is sodium-independent. It has a higher affinity for adenosine. Inhibited by dipyridamole and dilazep (anticancer chemotherapeutics drugs).
Subcellular Location Basolateral cell membrane; Multi-pass membrane protein. Apical cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Note=Predominantly localized in the basolateral membrane in polarized MDCK cells.
Tissue Specificity Detected in erythrocytes (at protein level). Expressed in heart, brain, mammary gland, erythrocytes and placenta, and also in fetal liver and spleen. {ECO:0000269|PubMed:12527552, ECO:0000269|PubMed:23219802}.
Top Pathways Alcoholism

ENT1 CRISPR/Cas9 KO Plasmid (h) - sc-401603 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ENT1 HDR Plasmid (h) - sc-401603-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ENT1 Double Nickase Plasmid (h) - sc-401603-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ENT1 Double Nickase Plasmid (h2) - sc-401603-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ENT1 CRISPR Activation Plasmid (h) - sc-401603-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ENT1 CRISPR Activation Plasmid (h2) - sc-401603-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ENT1 Lentiviral Activation Particles (h) - sc-401603-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ENT1 Lentiviral Activation Particles (h2) - sc-401603-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ENT1 siRNA (h) - sc-60583 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ENT1 shRNA Plasmid (h) - sc-60583-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ENT1 shRNA (h) Lentiviral Particles - sc-60583-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ENT1 RNAi - H00002030-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU088691 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN19540 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19540 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR05620 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr05620

SLC29A1 siRNA (Human) - CRH1409 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SLC29A1 - MBS8222017 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human SLC29A1 (NM_004955.2) - SHH410148 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human SLC29A1(NM_004955.2) - SHL004990 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human SLC29A1(NM_001078174.1) - SHL005272 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human SLC29A1(NM_004955.2) - SHL005326 from Creative biogene

Category siRNA
Species Reactivities Human

Human SLC29A1 siRNA - orb261911 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SLC29A1 shRNA Plasmid (Human) - CHH1409 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

SLC29A1 miRNA 3'UTR clone - MiUTR1H-09508 from Creative biogene

Species Reactivities Human
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