| Gene Symbol |
ASIC5
|
| Entrez Gene |
51802
|
| Alt Symbol |
ACCN5, HINAC, INAC
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
acid sensing (proton gated) ion channel family member 5
|
| Other Description |
acid-sensing (proton-gated) ion channel family member 5|acid-sensing ion channel 5|amiloride-sensitive cation channel 5, intestinal|amiloride-sensitive sodium channel|human intestine Na(+) channel
|
| Swissprots |
Q9NY37
|
| Accessions |
EAX04887 Q9NY37 AJ252011 CAB85607 BC140356 AAI40357 BC146497 AAI46498 NM_017419 NP_059115
|
| Function |
Cation channel that gives rise to very low constitutive currents in the absence of activation. The activated channel exhibits selectivity for sodium, and is inhibited by amiloride. {ECO:0000269|PubMed:10767424}.
|
| Subcellular Location |
Cell membrane {ECO:0000269|PubMed:10767424}; Multi-pass membrane protein {ECO:0000269|PubMed:10767424}.
|
| Tissue Specificity |
Detected in small intestine, duodenum and jejunum. Detected at very low levels in testis and rectum. {ECO:0000269|PubMed:10767424}.
|
| Top Pathways |
Inflammatory mediator regulation of TRP channels
|
![Western Blot: ACCN5 Overexpression Lysate (Adult Normal) [NBP2-06981] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for ACCN5.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/4927_ACCN5%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-06981-img0001.jpg)