Gene Symbol | ASIC5 |
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Entrez Gene | 51802 |
Alt Symbol | ACCN5, HINAC, INAC |
Species | Human |
Gene Type | protein-coding |
Description | acid sensing (proton gated) ion channel family member 5 |
Other Description | acid-sensing (proton-gated) ion channel family member 5|acid-sensing ion channel 5|amiloride-sensitive cation channel 5, intestinal|amiloride-sensitive sodium channel|human intestine Na(+) channel |
Swissprots | Q9NY37 |
Accessions | EAX04887 Q9NY37 AJ252011 CAB85607 BC140356 AAI40357 BC146497 AAI46498 NM_017419 NP_059115 |
Function | Cation channel that gives rise to very low constitutive currents in the absence of activation. The activated channel exhibits selectivity for sodium, and is inhibited by amiloride. {ECO:0000269|PubMed:10767424}. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:10767424}; Multi-pass membrane protein {ECO:0000269|PubMed:10767424}. |
Tissue Specificity | Detected in small intestine, duodenum and jejunum. Detected at very low levels in testis and rectum. {ECO:0000269|PubMed:10767424}. |
Top Pathways | Inflammatory mediator regulation of TRP channels |
ACCN5 CRISPR/Cas9 KO Plasmid (h) - sc-409956 from Santa Cruz Biotechnology
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ACCN5 HDR Plasmid (h) - sc-409956-HDR from Santa Cruz Biotechnology
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ACCN5 Double Nickase Plasmid (h) - sc-409956-NIC from Santa Cruz Biotechnology
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ACCN5 Double Nickase Plasmid (h2) - sc-409956-NIC-2 from Santa Cruz Biotechnology
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ACCN5 CRISPR Activation Plasmid (h) - sc-409956-ACT from Santa Cruz Biotechnology
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ACCN5 CRISPR Activation Plasmid (h2) - sc-409956-ACT-2 from Santa Cruz Biotechnology
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ACCN5 Lentiviral Activation Particles (h) - sc-409956-LAC from Santa Cruz Biotechnology
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ACCN5 Lentiviral Activation Particles (h2) - sc-409956-LAC-2 from Santa Cruz Biotechnology
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ACCN5 siRNA (h) - sc-89214 from Santa Cruz Biotechnology
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ACCN5 shRNA Plasmid (h) - sc-89214-SH from Santa Cruz Biotechnology
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ACCN5 shRNA (h) Lentiviral Particles - sc-89214-V from Santa Cruz Biotechnology
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ACCN5 RNAi - H00051802-R01 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN2711 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2711 from Sigma-Aldrich
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ASIC5 siRNA (Human) - CRH9948 from Cohesion Biosciences
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ASIC5 - MBS8227740 from MyBioSource
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shRNA set against Human ACCN5 (NM_017419.2) - SHH230158 from Creative biogene
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shRNA set against Human ACCN5(NM_017419.2) - SHG029395 from Creative biogene
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Human ASIC5 siRNA - orb270450 from Biorbyt
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ASIC5 shRNA Plasmid (Human) - CHH9948 from Cohesion Biosciences
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ASIC5 miRNA 3'UTR clone - MiUTR1H-00097 from Creative biogene
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